William Franklin "Frank" Knox (January 1, 1874 – April 28, 1944) was an American newspaper editor and publisher. He was also the Republican vice presidential candidate in 1936, and Secretary of the Navy under Franklin D. Roosevelt during most of World War II.
William Franklin Knox was born in Boston, Massachusetts. His parents were both Canadian: his father was from New Brunswick and his mother Sarah Barnard, was from Charlottetown, Prince Edward Island. When he was nine, his family moved to Grand Rapids, Michigan, where his father ran a grocery store. He attended Alma College in Michigan, where he was a member of the Zeta Sigma Fraternity.
During the Spanish-American War, he joined the Army, and served in Cuba with the Rough Riders .
After the war, Knox became a newspaper reporter in Grand Rapids. This was the beginning of a career that included ownership of several papers.
He changed his first name to Frank around 1900. In 1912 as founding editor of New Hampshire's Manchester Leader, forerunner to the New Hampshire Union Leader, he supported Theodore Roosevelt's Progressive ticket. However, with that exception, he adhered to the Republican Party.