BAR (Bin–Amphiphysin–Rvs) domains are highly conserved protein dimerisation domains that occur in many proteins involved in membrane dynamics in a cell. The BAR domain is banana shaped and binds to membrane via its concave face. It is capable of sensing membrane curvature by binding preferentially to curved membranes. The occurrence in different protein and more information can be found on endocytosis.org.

Many BAR family proteins contain alternative lipid specificity domains that help target these protein to particular membrane compartments. Some also have SH3 domains that bind to dynamin and thus proteins like amphiphysin and endophilin are implicated in the orchestration of vesicle scission.

Some BAR domain containing proteins have an N-terminal amphipathic helix preceding the BAR domain. This helix inserts (like in the epsin ENTH domain) into the membrane and induces curvature, which is stabilised by the BAR dimer. Amphiphysin, endophilin, BRAP1/bin2 and nadrin are examples of such proteins containing an N-BAR. The Drosophila amphiphysin N-BAR (DA-N-BAR) is an example of a protein with a preference for negatively charged surfaces.

Steve Hiroyuki Aoki (born November 30, 1977) is an American electro house musician, record producer and the founder of Dim Mak Records.

Steve Hiroyuki Aoki was born in Miami and grew up in Newport Beach, California. He graduated from Newport Harbor High School in 1995; he was a star player on the varsity badminton team. He is the third child of Rocky Aoki and Chizuru Kobayashi. His father was a former Japanese Olympic wrestler who also founded the restaurant chain Benihana. He has two older siblings, sister Kana (who is sometimes called by her middle name "Grace"), and brother Kevin (owner of Doraku Sushi restaurant). He also has three half-siblings, all of whom are younger: half-brother Kyle and half-sisters Echo, and Devon, the supermodel and actress. As a child, Steve lived with his grandfather,^{[citation needed]} his mother, and his two older siblings.

Aoki attended the University of California, Santa Barbara and graduated with two B.A.s; one in Women's Studies and the other in Sociology. In college, he produced do-it-yourself records and ran underground concerts out of his Biko room in the Santa Barbara Student Housing Cooperative, which was located in Isla Vista, a section of residential land adjacent to UCSB. As a concert venue, the apartment became known as The Pickle Patch. By his early 20s, Aoki had built his own record label, which he named Dim Mak after his childhood hero, Bruce Lee. He has also been in numerous bands, including This Machine Kills, which released an album on Ebullition Records, Esperanza, and The Fire Next Time.