- published: 23 Oct 2013
- views: 9530
L-DOPA (/ˌɛlˈdoʊpə/ or levodopa /ˌlɛvoʊˈdoʊpə/) (alt., L-3,4-dihydroxyphenylalanine) is a chemical that is made and used as part of the normal biology of humans, some animals and plants. Some animals and humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines. Furthermore, L-DOPA itself mediates neurotrophic factor release by the brain and CNS.L-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Pharmacopa, Atamet, Stalevo, Madopar, and Prolopa. As a drug, it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.
L-DOPA has a counterpart with opposite chirality, D-DOPA. As is true for many molecules, the human body produces only one of these isomers (the L-DOPA form). The enantiomeric purity of L-DOPA may be analyzed by determination of the optical rotation or by chiral thin-layer chromatography (tlc).
I've got life
one more time
i leave behind just burning bridges
it's a crime
i am here
there must be somewhere i can breathe
now take me there
It's time to see
i wanna make you breathe
that life can be me whatever
what you want it to be
you need the key
i'm gonna make you see
no more make believe
you just go
I've got life
you're always on my mind
you gotta believe in something, alright
forever by your side
i've got life
just give me time to find
whatever it is, it will be alright
forever by your side
i've got life
I've got life
What's that sound
my destiny is bound for changes
lost and found
you tell me
there's gonna be a showdown somewhere
it's irit
It's time to see
i'm gonna make you see
no more make believe
you just go
I've got life
you're always on my mind
you gotta believe in something, alright
forever by your side
i've got life
just give me time to find
whatever it is, it will be alright
forever by your side
i've got life
I've got life
I've got life
alright
you gotta believe in something, alright
i'm by your side
We're gonna live forever
don't let this be whatever
i'm gonna make you believe in something, 'cause
we're gonna live forever
if you never say never
we're gonna make it alright
I've got life
you're always on my mind
you gotta believe in something alright
forever by your side
i've got life
just give me time to find
whatever it is it will be alright
forever by your side