Federico is a given name and surname.

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Federico, Visigoth general and brother of Theodoric II who died at the Battle of Orleans

Luis Federico Leloir FRS (September 6, 1906 – December 2, 1987) was an Argentine doctor and biochemist who received the 1970 Nobel Prize in Chemistry. He was the first Spanish-speaking scientist to ever receive the award. Although born in France, Leloir received the majority of his education at the University of Buenos Aires and was director of the private research group Fundación Instituto Campomar until his death in 1987. Although his laboratories were often plagued by lack of financial support and second-rate equipment, his research into sugar nucleotides, carbohydrate metabolism, and renal hypertension has garnered international attention and fame and has led to significant progress in understanding, diagnosing and treating the congenital disease galactosemia. Luis Leloir is buried in La Recoleta Cemetery, Buenos Aires.

Leloir's parents, Federico Leloir and Hortensia Aguirre de Leloir, traveled from Buenos Aires to Paris in the middle of 1906 with the intention of treating Federico's illness. However, Federico died in late August, and a week later Luis was born in an old house at 81 Víctor Hugo Road in Paris, a few blocks away from the Arc de Triomphe. After returning to Argentina in 1908, Leloir lived together with his eight siblings on their family's extensive property El Tuyú that his grandparents had purchased after their immigration from the Basque Country of northern Spain: El Tuyú comprises 400 km² of rocky land that along the coastline from San Clemente del Tuyú to Mar de Ajó which has since become a popular tourist attraction.