The Nintendo Vs. System is a coin-operated video game platform designed for two-player competitive play using the VS. UniSystem or VS. DualSystem, arcade system boards based on the Nintendo Entertainment System. Many of these stand-up or sit-down arcade machines had two screens and controls joined at an angle. These games were arcade ports of home video games for the Nintendo Entertainment System, thus they could be sold cheaply to arcades in the late 1980s.

The Vs. System was designed primarily as a kit to retrofit Donkey Kong, Donkey Kong Jr., Popeye, and Mario Bros. machines. Being as such, they require the same special monitor that these coin-ops used. These monitors use inverse voltage levels for their video signals as compared to most arcade monitors. Commercially available converters allowed one to use any standard open frame monitor with the game.

Almost all the games on the Vs. System ran on identical hardware, with the notable exception that four special PPUs (video chips) were also made, each containing a different palette (each of which appears to arrange the colors completely randomly). Most boards could be switched to a new game simply by swapping the program ROMs, though the appropriate PPU would also have to be used—if not, the game would appear with incorrect colors. Several of the later Vs. games employed further measures of protection by using special PPUs which swapped pairs of I/O registers and/or returned special data from normally unimplemented regions of memory—attempts to run these games in other Vs. systems would result in the game failing to even start.

Vs. System (short for Versus System), also written as VS System and abbreviated as VS, is a collectible card game (CCG) designed by Upper Deck Entertainment (UDE). In the game, players build and play a deck of Vs. System cards in an attempt to win a game against their opponent. It was first published in 2004 and is set in the superhero genre. The game was discontinued by Upper Deck Entertainment in January 2009.

The sets of the Vs. System are based on the superheroic settings of Marvel and DC Comics, with the exception of a smaller set called the Hellboy Essential Collection. For the most part expansion sets alternated release between Marvel based sets and DC Comics based sets with new sets every three to six months. All sets are interchangeable and compatible with each other and share the same card back. This allows players to mix characters fighting against or with each other.

Card art, characters, and gameplay concepts are inspired by their comic book appearances with the designers using what they describe as "top-down design", meaning they make every attempt to develop a character's card mechanics in keeping with how the character is represented in comic books. Well known artists that have contributed card art include Alex Ross, John Van Fleet, Alex Garner, Jim Lee, Rachel Dodson, and Bill Sienkiewicz.