Dong Fangzhuo (Chinese: 董芳卓; pinyin: Dǒng Fāngzhuō; born 23 January 1985 in Dalian, Liaoning) is a Chinese footballer who plays as a forward for Hunan Xiangtao in the China League One.

Dong first came to prominence in 2000 when he was named Player of the Tournament in an U-17 football competition. He signed for Dalian Saidelong and helped them to finish as runners-up in the Chinese B League in 2002. This earned him selection to the Chinese Under-23 national team, and a move to Dalian Shide, the most successful club team in China. Dong scored his first goal for Dalian Shide in the second match of the qualifying stages of the 2002–03 AFC Champions League.

Dong signed for Manchester United from Dalian Shide in January 2004, for an initial fee of £500,000 which could have risen to £3.5 million, depending upon appearances. He thus became the first Chinese player to sign for Manchester United.

After signing for Manchester United, he was unable to play for the senior team immediately because he was ineligible for a work permit. Due to these legal issues, Dong was loaned out to get first-team experience at Royal Antwerp in Belgium where the employment laws were less strict.