Extispicy (from Latin extispicium) is the practice of using anomalies in animal entrails to predict or divine future events.Organs inspected include the liver, intestines, and lungs. The animal used for extispicy must often be ritually pure and slaughtered in a special ceremony.^{[citation needed]}

The practice was first common in ancient Mesopotamian, Hittite and Canaanite temples.^{[citation needed]} Later, soothsayers from Ancient Roman times used the entrails of a bull to determine the advisability of a particular endeavor and Etruscans used patterns seen in the livers of sheep to assess their future. There exists substantial evidence to indicate that this was the main form of divination within classical cultures.

Organ models and extispicy manuals in cuneiform script are widely found in archaeological excavations in the regions, showing the prevalence and significance of extispicy. Commonly, (in antiquity) the majority of the divination was wrought from viewing the intestines and the liver.