- published: 17 Jun 2017
- views: 539
Y chromosome microdeletion (YCM) is a family of genetic disorders caused by missing gene(s) in the Y chromosome. Many men with YCM exhibit no symptoms and lead normal lives. However, YCM is also known to be present in a significant number of men with reduced fertility. Men with reduced sperm production (in up to 20% of men with reduced sperm count, some form of YCM has been detected) varies from oligozoospermia, significant lack of sperm, or azoospermia, complete lack of sperm.
The mechanism of mutation is not different for Y-chromosome microdeletion. However, the ability to repair it differs from other chromosomes. The human Y chromosome is passed directly from father to son, and is not protected against accumulating copying errors, whereas other chromosomes are error corrected by recombining genetic information from mother and father. This may leave natural selection as the primary repair mechanism for the Y chromosome.
Y chromosome microdeletion is currently diagnosed by extracting DNA from leukocytes in a man's blood sample, mixing it with some of the about 300 known genetic markers for sequence-tagged sites (STS) on the Y chromosome, and then using polymerase chain reaction amplification and gel electrophoresis in order to test whether the DNA sequence corresponding to the selected markers is present in the DNA.
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New Music "Emmanuel Macron" performed by Dpsy, Blaike & Gee James (YCM) 2o17 Young Ceo Musique Director: RDLP Clipmakerz Montage: RDLP Clipmakerz Scénario: Young Ceo Musique Mixing: Djibril"Dpsy"Salah, Michel"Blaike"Nzuzi Link: https://soundcloud.com/young-ceo-musique-1/ycm-emmanuel-macron Social Network/Réseaux Sociaux: Facebook: https://www.facebook.com/young.ceo.musique/ Twitter: https://twitter.com/YoungCeoMusique Instagram: https://www.instagram.com/youngceomusique/ SoundCloud: https://soundcloud.com/young-ceo-musique-1 Email: young.ceo.musique75@gmail.com
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New Music "Bad Gal" performed by Dpsy, Blaike & Gee James (YCM) featuring Full PROD BY "Superstar O" 2o16 Young Ceo Musique Dir: RDLP CLIPMAKERZ Montage: RDLP CLIPMARKERZ Scénario: Young Ceo Musique Prod : Superstar O Link: https://soundcloud.com/young-ceo-musique-1/dpsy-x-blaike-x-gee-james-ycm-feat-full-bad-gal Social Network/Réseaux Sociaux: Facebook: https://www.facebook.com/young.ceo.musique/ Twitter: https://twitter.com/YoungCeoMusique Instagram: https://www.instagram.com/youngceomusique/ SoundCloud: https://soundcloud.com/young-ceo-musique-1 Email: young.ceo.musique75@gmail.com
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