Tau Kappa Epsilon (ΤΚΕ or Teke, pronounced T-K-E or /ˈtiːk/) is a college fraternity founded on January 10, 1899 at Illinois Wesleyan University with chapters in the United States, and Canada, and affiliation with a German fraternity system known as the Corps of the Weinheimer Senioren Convent (WSC). There are currently 292 active TKE chapters and colonies throughout the United States and Canada, the largest fraternity in the world chapter wise. The colors of the fraternity are the shade of cherry known as crimson lake, and the shade of gray known as pure silver. Of the national fraternities founded prior to 1920, TKE is one of the few fraternities that never had a discrimination clause in its membership requirements to prevent membership of men because of their race, color, or creed. TKE was also one of the first fraternities to abolish "Hell week" when in 1928 it was replaced with an initiation period consisting of lessons portraying the finest attributes of brotherhood. Some notable members of Tau Kappa Epsilon are: founder of Walgreen, Charles Walgreen, 40th President of the United States, Ronald W. Reagan, legendary singer, entertainer and actor, Elvis Aaron Presley an honorary member in 1960, founder of Starbucks, Howard Schultz, founder of the NFL and former owner and coach of the Chicago Bears, George S. Halas, and inventor of the electric guitar, Les Paul.

Kappa Epsilon (KΕ) is a professional pharmacy fraternity founded by Zada M. Cooper on May 13, 1921. It was founded with the purpose of uniting female pharmacy students in an era when women were a minority in the profession. Today, KE has 38 collegiate chapters and 10 alumni chapters. Over 20,000 women and men have been initiated into KE since its founding.

Kappa Epsilon's National Project is the promotion of breast cancer awareness. Many KE chapters participate in the Race for the Cure or Relay For Life. KE chapters are also encouraged to promote awareness of other women's health issues such as osteoporosis. KE's recently added the Pharmacy Career Opportunity Recruitment Project (Pharm-CORP) to their National Project. Pharm-CORP works to introduce pharmacy careers to middle and high school aged students and encourages them to excel in math and the sciences.

Kappa Epsilon sponsors one scholarship and one fellowship. The Zada Cooper Scholarship, named for the fraternity's founder, is given to six students every year. The Nellie Wakeman Fellowship is given to a member in his/her last year of pharmacy school who wishes to pursue graduate study. For both awards, the recipient must be a fraternity member in good standing.