The New Deal Coalition was the alignment of interest groups and voting blocs that supported the New Deal and voted for Democratic presidential candidates from 1932 until the late 1960s. It made the Democratic Party the majority party during that period, losing only to Dwight D. Eisenhower in 1952 and 1956. Franklin D. Roosevelt forged a coalition that included the Democratic state party organizations, city machines, labor unions and blue collar workers, minorities (racial, ethnic and religious), farmers, white Southerners, people on relief, and intellectuals. The coalition fell apart around the bitter factionalism during the 1968 election, but it remains the model that party activists seek to replicate.

The 1932 presidential election and the 1934 off-year elections brought about long-term shifts in voting behavior, and became a permanent realignment. Roosevelt set up his New Deal in 1933 and forged a coalition of labor unions, liberals, ethnic and racial minorities (Catholics, Jews and Blacks), Southern whites, poor people and those on relief. The organizational heft was provided by Big City machines, which gained access to millions of relief jobs and billions of dollars in spending projects. These voting blocs together formed a majority of voters and handed the Democratic Party seven victories out of nine presidential elections (1932–36-40-48, 1960, 1964), as well as control of both houses of Congress during all but 4 years between the years 1932-1980 (Republicans won small majorities in 1946 and 1952). Starting in the 1930s, the term “liberal” was used in U.S. politics to indicate supporters of the coalition, while "conservative" denoted its opponents. The coalition was never formally organized, and the constituent members often disagreed. The coalition usually supported liberal proposals in domestic affairs, but was less united in terms of foreign policy and racial issues.