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Synergy Pharmaceuticals Presents New Plecanatide Phase 3 Data in Chronic Idiopathic Constipation at Digestive Disease Week (Synergy Pharmaceuticals Inc)

Edit Public Technologies 24 May 2016
(Source. Synergy Pharmaceuticals Inc). NEW YORK-- Synergy Pharmaceuticals Inc ... Data were presented at Digestive Disease Week (DDW) in San Diego. 'These data show that plecanatide has the potential to address the serious unmet need for people with CIC,' said Lead Investigator Philip B ... Rates of discontinuation due to treatment-emergent AEs were 3.2% in 3mg and 3.8% in 6mg dose groups compared to 3.0% in the placebo group ... About Plecanatide....

Edison Investment Research Report maintains valuation as Novogen resumes 100% ownership of Cantrixil (Novogen Limited)

Edit Public Technologies 10 May 2016
(Source. Novogen Limited) Edison Research Template Novogen Clinical update. Cantrixil to enter clinic in H216 ... 0.3 ... Exhibit 1 shows that Anisina at 100mg/kg and docetaxel at 3mg/kg were equally effective at inhibiting tumour growth when used as single agents ... The low toxicity of Anisina is illustrated in Exhibit 2, which shows that mice treated with Anisina at 100mg/kg put on much more weight than those treated with docetaxel at 3mg/kg,....

Bitter pill for diabetics?

Edit The Hindu 03 May 2016
If there is such a thing as a Richter scale for the Indian pharmaceutical industry, then the Centre’s announcement in March banning a clutch of Fixed Dose Combinations (FDC) did register pretty high on it. There was a hue and cry from a vibrant industry employing all manner and form of combinations in the manufacture of drugs ... A ... Panneerselvam adds ... A ... Pill fatigue ... Gliclazide 40/80mg + Metformin 500/1000mg + Voglibose 0.2mg/ 0.3mg....

Regeneron Announces Positive Topline Results from Phase 2/3 Fasinumab Study in Patients with Osteoarthritis Pain (Regeneron Pharmaceuticals Inc)

Edit Public Technologies 02 May 2016
(Source ... (NASDAQ ... The U.S ... fasinumab 1mg, 3mg, 6mg, 9mg, or placebo, all delivered subcutaneously every 4 weeks through week 12, with the primary efficacy measured at week 16 ... Placebo ... During the study period there were no cases of ON, there was 1 case of SIF in placebo, 0, 2, 0 and 4 cases of SIF in the 1mg, 3mg, 6mg, and 9mg fasinumab dose groups respectively, and 1 case of RPOA in each of the 3mg, 6mg, and 9mg fasinumab dose groups....

Water from 161 sources unfit for drinking: ZP

Edit The Times of India 29 Apr 2016
Nashik. Deficit rainfall last year and souring temperatures this summer have led to drastic fall in the district's groundwater levels ... "High levels of fluoride content in water leads to pitting of tooth enamel and its deposits in bones," said officials of the Nashik ZP ... However, the flouride content was been found to be 9.9 mg/litre in Yeola, 7.3mg/litre in Deola and 3.1 mg/litre in Chandwad ... ....

River water in state not safe for drinking: Arukha

Edit The Times of India 27 Apr 2016
Bhubaneswar. State forest and environment minister Bikram Keshari Arukha on Tuesday told the assembly that water in none of 11 major rivers or their tributaries in the state were suitable for drinking ... He added that Kathajodi river in Cuttack and Daya river in Bhubaneswar were among the worst-polluted rivers with very high BOD and TC levels ... Similarly, BOD up to 3mg/litre and TC up to 500 microbes per millilitre can be used for bathing....

Schizophrenia Issues

Edit PsychCentral 23 Apr 2016
Hello, First and foremost I am currently starting psychiatric care again after 7 years with a view to changing/increasing my medication. I am currently taking rispirodone 3mg once a day and I have been for 7 years ... It is a constant battle of good and bad and how i should lead my life and how i should feel about other people and situations ... A ... Discuss your options with your prescribing physician ... Dr....

Stawell car yard hit by burglars (Victoria Police)

Edit Public Technologies 19 Apr 2016
(Source. Victoria Police) ... Investigators have been told that the burglars stole a new white Ford Ranger, a red 2011 Ford GT-P sedan, a 2002 grey car trailer and a set of number plates bearing registration number 1FT 3MG ... Creina O'Grady. Media Officer. 49204/2016 ... Original Document....

European Commission Approves Expanded Use of Opdivo® (nivolumab) to Include Previously Treated Metastatic Non-Squamous Non-Small Cell Lung Cancer (131KB) (ONO Pharmaceutical Co Ltd)

Edit Public Technologies 13 Apr 2016
(Source ... April 13, 2016 ... In Japan, Ono Pharmaceutical Co., Ltd ... CheckMate -017 is a landmark, Phase 3, open-label, randomized clinical trial that evaluated Opdivo 3mg/kg intravenously over 60 minutes every two weeks versus standard of care, docetaxel 75 mg/m2 intravenously administered every three weeks in patients with advanced squamous NSCLC who had progressed during or after one prior platinum doublet-based chemotherapy regimen ... Ltd....

European Commission Approves Expanded Use of Opdivo® (nivolumab) to Include Previously Treated Metastatic Non-Squamous Non-Small Cell Lung Cancer (Bristol-Myers Squibb Company)

Edit Public Technologies 06 Apr 2016
(Source. Bristol-Myers Squibb Company) ... 33.3-44.6) ... 33.3-44.6) ... CheckMate -017 is a landmark, Phase 3, open-label, randomized clinical trial that evaluated Opdivo 3mg/kg intravenously over 60 minutes every two weeks versus standard of care, docetaxel 75 mg/m2 intravenously administered every three weeks in patients with advanced squamous NSCLC who had progressed during or after one prior platinum doublet-based chemotherapy regimen ... U.S....

Advaxis Combination Trial with MedImmune Completes First Dose-Escalation Cohort (Advaxis Inc)

Edit Public Technologies 29 Mar 2016
(Source. Advaxis Inc). Study Commences Second Dose-Escalation Cohort. 90-Patient Phase II Combination Trial in Cervical and Head and Neck Cancer to Begin Mid-Year. PRINCETON, N.J., March 29, 2016 (GLOBE NEWSWIRE) -- Advaxis, Inc ... The first dose-escalation cohort evaluated AXAL at 1x10 cfu with 3mg/kg durvalumab and the second dose-escalation cohort will now examine AXAL at 1x10 cfu in combination with 10mg/kg durvalumab ... durvalumab alone....

Ban on 343 drugs to hit diabetics the hardest, say endocrinologists

Edit DNA India 20 Mar 2016
--> ... The government had banned the drugs via a notification on March 12 following recommendations of an expert committee formed to examine the efficacy of selected combinations ... "Most of these patients are taking multiple medicines because of secondary illnesses ... Glimepiride 1mg/2mg/3mg + Pioglitazone 15mg/15mg/15mg + Metformin 1,000mg/1,000mg/1,000mg ... Metformin (sustained release) 500mg + Pioglitazone 15 mg + Glimepiride 3mg ... Info ... ....

Allergan Announces U.S. Availability of VRAYLAR™ (cariprazine) for Treatment of Bipolar Mania and Schizophrenia in Adults

Edit PR Newswire 16 Mar 2016
DUBLIN, March 16, 2016 /PRNewswire/ -- Allergan plc (NYSE. AGN), a leading global pharmaceutical company, announced today that VRAYLAR™ (cariprazine), a once-daily oral atypical antipsychotic, is now available by prescription in pharmacies throughout the U.S ... VRAYLAR will be commercially available in 30 count bottles in 1.5mg, 3mg, 4.5mg and 6mg and a 7 count mixed blister pack (one 1.5mg and six 3mg tablets).  ... and Canada ... ....
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