Daniela Garnero Santanchè (Italian pronunciation: [daˈnjɛːla santaŋˈkɛ]) (born 7 April 1961) is an Italian entrepreneur and a politician. She was Undersecretary to the Minister of Platform Accomplishment from 2010 to 2011 during Berlusconi IV Cabinet.
Christened Daniela Garnero, Santanchè was born in Cuneo, Piedmont. She moved to Turin to study political science, and at 21 married Paolo Santanchè, a plastic surgeon. She was employed by his company in an administrative role.
After studying political science, in 1983 she founded a company that focused on marketing. She later acquired shares of the Billionaire company, along with Flavio Briatore, Lele Mora, Paolo Brosio and Marcello Lippi.
In 1995, she left her husband, Paolo Santanchè, and began a relationship with Canio Mazzaro, a pharmaceutical entrepreneur from Potenza. Her marriage to Paolo Santanchè was declared void by the Roman Rota. In politics she has continued to use the Santanchè surname, despite an unsuccessful court case by her ex-husband to try to stop her. Her current partner is the journalist Alessandro Sallusti, editor of il Giornale, a daily newspaper owned by Paolo Berlusconi and Vittorio Feltri.