- published: 21 Aug 2015
- views: 287018
COPI is a protein complex that coats vesicles transporting proteins from the cis end of the Golgi complex back to the rough endoplasmic reticulum (ER), where they were originally synthesized, and between Golgi compartments. This type of transport is termed as retrograde transport, in contrast to the anterograde transport associated with the COPII protein. The name "COPI" refers to the specific coat protein complex that initiates the budding process on the cis-Golgi membrane. The coat consists of large protein subcomplexes that are made of seven different protein subunits.
Coat protein, or COPI, is an ADP ribosylation factor (ARF)-dependent adaptor protein involved in membrane traffic. COPI was first identified in retrograde traffic from the cis-Golgi to the rough endoplasmic reticulum (ER) and is the most extensively studied of ARF-dependent adaptors. COPI consists of seven subunits which compose the heptameric protein complex.
The primary function of adaptors is the selection of cargo proteins for their incorporation into nascent carriers. In the case of the adaptor COPI, cargo containing the sorting motif KKXX interact with COPI to form carriers which are transported from the cis-Golgi to the rough ER. Current views suggest that ARFs are also involved in the selection of cargo for incorporation into carriers.
Grand Theft Auto V is an open world, action-adventure video game developed by Rockstar North and published by Rockstar Games. It was released on 17 September 2013 for the PlayStation 3 and Xbox 360, on 18 November 2014 for the PlayStation 4 and Xbox One, and on 14 April 2015 for Microsoft Windows. The game is the first main entry in the Grand Theft Auto series since 2008's Grand Theft Auto IV. Set within the fictional state of San Andreas, based on Southern California, the single-player story follows three criminals and their efforts to commit heists while under pressure from a government agency. The open world design lets players freely roam San Andreas's open countryside and fictional city of Los Santos, based on Los Angeles.
The game is played from either a first-person or third-person view and its world is navigated on foot or by vehicle. Players control the three lead protagonists throughout single-player and switch between them both during and outside of missions. The story is centred on the heist sequences, and many missions involve shooting and driving gameplay. A "wanted" system governs the aggression of law enforcement response to players who commit crimes. Grand Theft Auto Online, the online multiplayer mode, lets up to 30 players explore the open world and engage in cooperative or competitive game matches.
The abbreviation G.T.A. may stand for:
Kindergarten Cop is a 1990 American comedy film directed by Ivan Reitman and starring Arnold Schwarzenegger as John Kimble, a tough police detective, who must go undercover and pose as a kindergarten teacher to catch drug dealer Cullen Crisp (Richard Tyson), before he can get to his former wife and son.
Along the way, he discovers his passion for teaching and considers changing his profession to become an educator. Pamela Reed plays his partner, Phoebe O'Hara, and Penelope Ann Miller plays Joyce, the teacher who becomes his love interest. The original music score was composed by Randy Edelman.
After years of pursuing drug lord Cullen Crisp (Richard Tyson), Los Angeles Police detective John Kimble (Schwarzenegger) has him on a murder charge after Crisp shot and killed an informant (Tom Kurlander) who has given him information regarding the whereabouts of his former wife, Rachel Myatt Crisp, and his son Cullen, Jr. However, the informant's girlfriend (Alix Koromzay) is unwilling to testify in court.
Episode I, Episode 1 or Episode One may refer to:
Actors: Cornelia Stefan (miscellaneous crew), Tobe Hooper (director), Andrew Cohen (editor), Jaye Gazeley (producer), BC Smith (composer), Daniela Tully (producer), Malik McCall (actor), Ahd (actress), Isa Swain (miscellaneous crew), Soumaya Akaaboune (actress), Tim Andrew (producer), Robert Crippen (producer), Khalid Laith (actor), Carol Abboud (actress), Maxine De Vere (miscellaneous crew),
Genres: Horror, Thriller,Actors: Darren Elliot Fulsher (actor), Tommy Martin (actor), Kyle Dal Santo (actor), Jesse Allen Michael Hibbs (actor), Jesse Allen Michael Hibbs (director), Jesse Allen Michael Hibbs (producer), Jesse Allen Michael Hibbs (writer), Melissa Walker (actress), Kalle Jogisoo (actor), Kalle Jogisoo (producer), Marcus Funches (actor), Keith Carmack (actor), Miriam Moore-Hunter (producer), Fernando Mexicano (editor), Drew Pientka (editor),
Genres: Crime, Drama, Short,Actors: Moby Gratis (composer), Preston Miller (editor), Preston Miller (director), Trey Albright (actor), Jodi Lin (producer), Jodi Lin (writer), Jodi Lin (actress), Kaitlyn Suen (actress), Louis So (actor), Miguel Cisneros (actor),
Genres: Biography, Short,Actors: Romeo Ryder (director), Kimberly Ann Saviano (producer), Steve Monarque (actor), Steve Monarque (director), Steve Monarque (writer), Armando Merlo (actor), Kelly Monarque (producer), Suzanne Cortney (actress), Suzanne Cortney (producer), Geoff Gormley (editor), Geoff Gormley (producer), Greg Hannley (producer), Ben Garner (actor), Dan Wiley (actor), Chris Kowanko (composer),
Genres: Drama, Short,Actors: Yeniffer Behrens (actress), Alvaro Orlando (actor), Gonzalo Gonzalez (producer), Carlos Pratts (actor), Kurt Caceres (actor), Pejman Partiyeli (producer), Kenneth Castillo (writer), Kenneth Castillo (director), Liz Lohof (producer), Tony Maggio (actor), Aurelio Bocanegra (actor), Carlos Melendez (editor), Alexis Tanasoca (miscellaneous crew), Andy Thompson (actor), Cesar Ramos (actor),
Genres: Action, Crime, Drama,Actors: Joseph Cintron (actor), Dana Glover (producer), Dana Glover (producer), Dana Glover (writer), Dana Glover (director), Dana Glover (composer), Michelle Carter (producer), Michelle Carter (editor), Michelle Carter (producer), Jesse Ferraro (actor), David Anderson (producer), David Anderson (actor), David Anderson (writer), Alexis Celeste Elliott (miscellaneous crew), Carolyn Hunt (producer),
Plot: Shoal Creek was always known as a safe and friendly place. The residents truly enjoyed its beautiful park and neighborhood bar. Just the kind of place Jeff Johnson, a troubled loner and the new owner of Shoal Creek bar was looking for. However, over the past 8 months things changed. With a string of grisly murders, this once peaceful paradise has suddenly been over taken with trepidation and genuine terror. A serial killer has also made Shoal Creek home. Kristi, an attractive and sometimes extremely flirtation woman, is on a secret rendezvous to meet a friend at Shoal Creek bar. The same bar that happens to be near the site of several unsolved murders. Her presence instantly draws the attention of a number of male clientèle. After rejecting their advances and with her friend being a no show, Kristi quickly discovers she's being hunted in a terrifying game of cat and mouse.
Keywords: erotica, serial-killer, suspense, terrorActors: Lee Abbott (actor), Lee Abbott (writer), Lee Abbott (director), Jeff M. Lewis (actor), Michael Sonntag (producer), John G. Coppola (producer), Jeri Zucchi (producer), Jeri Zucchi (writer), Michael Oden (actor), Michael Oden (writer), Micheal Oden (actor),
Genres: Drama, Short,Actors: Barry Otto (actor), Aash Aaron (actor), Chris Haywood (actor), Robert Coleby (actor), Miranda Otto (actress), Shaun Micallef (actor), Graeme Blundell (actor), Steven Vidler (actor), Jerome Ehlers (actor), Barbara Gibbs (producer), Peter O'Brien (actor), Mikael Borglund (producer), Damien Garvey (actor), Paul Sonkkila (actor), John Stanton (actor),
Genres: Drama,Actors: Michael J. Reynolds (actor), Gabrielle Rose (actress), Hrothgar Mathews (actor), Ralph Brunjes (editor), Ken Pogue (actor), Tanya Mazur (miscellaneous crew), Ian Tracey (actor), Roger Dunn (actor), Laszlo Barna (producer), Garwin Sanford (actor), John McCarthy (composer), Darcy Fehr (actor), Sabrina Grdevich (actress), Robert Huculak (actor), Jon Ted Wynne (actor),
Plot: This film tells the story of David Milgaard, who was charged and convicted for a brutal rape & murder he did not commit. Sentenced to life imprisonment, he must struggle to survive in his years in prison, while his family and two crusading lawyers struggle to prove his innocence.
Keywords: canada, courtroom, false-accusation, miscarriage-of-justice, murder, prison, wrongful-convictionActors: Lindsay Wagner (actress), John Ireland (actor), George Buza (actor), Karen Black (actress), Saul Rubinek (actor), R.H. Thomson (actor), Richard Blackburn (actor), Eugene Clark (actor), James Coburn (actor), J. Winston Carroll (actor), Richard Donat (actor), Philip Akin (actor), Richard Harris (actor), Blanche McDermaid (miscellaneous crew), Simon Reynolds (actor),
Plot: Threatened with recapture after a prison escape, Martin Stechert grabs a 12-year-old as hostage. He proves to be named Martin, too - a quiet "good little boy" always obeying the rules, whom life has given only dismal loneliness and frustration in return. Soon he begins to admire "Stech" for his cheeky pranks against society and his desperate mission to make dreams come true. In a climactic moment, he chooses to stay with the man even though he could run away. Via hijacks and hijinx, they flee to the idyllic peace of the older Martin's childhood home, a cabin on a lake. But the police are close behind, impatient and trigger-happy.
Keywords: character-name-in-title, child-driving-car, escape, hostage, independent-film, intergenerational-friendship, kidnapper-kidnapped-relationship, prisonIf you'd like to see more you can subscribe here! -https://goo.gl/1ldLPx Snapchat- ADayWithKev Twitter- http://www.Twitter.com/KevinEdwardsJr Instagram- http://www.Instagram.com/KevinEdwardsJr Facebook- http://www.Facebook.com/KevinEdwardsJrPage
Subscribe to TRAILERS: http://bit.ly/sxaw6h Subscribe to COMING SOON: http://bit.ly/H2vZUn Like us on FACEBOOK: http://goo.gl/dHs73 Follow us on TWITTER: http://bit.ly/1ghOWmt Paul Blart: Mall Cop 2 Official Trailer #1 (2015) - Kevin James, David Henrie Sequel HD The sequel follows James' Paul Blart who attends a Security Guard Expo in Las Vegas with his daughter. Despite being teased by casino security and other attendees, Blart takes on a group of dangerous art thieves. The Movieclips Trailers channel is your destination for the hottest new trailers the second they drop. Whether it's the latest studio release, an indie horror flick, an evocative documentary, or that new RomCom you've been waiting for, the Movieclips team is here day and night to make sure all the best new movie trailer...
GTA 5 PC mods gameplay max settings 1080p free roam livestream includes first person mode SAPD:FR / LSPD:FR police simulator mode gameplay for Grand Theft Auto 5 PC in HD. This GTA 5 gameplay includes GTA 5 PC mods gameplay and funny moments in Grand Theft Auto V showcasing the play as a police patrol mod where you wear the police outfit, go on police chases and engage in shootouts! ► Help Me Reach 1,500,000 Subscribers! Click to Subscribe! ► http://bit.ly/SubToTG Spreadshirt Shops: ● US Shop - http://typicalgamer.spreadshirt.com ● UK Shop - http://typicalgamer.spreadshirt.co.uk ● EU Shop - http://typicalgamer-eu.spreadshirt.net GTA 5 PC SAPD:FR Alpha mod: http://www.palmbeachgames.com/files/file/3-sapdfr/ Join Team TG and subscribe today: http://bit.ly/SubToTG ● Add me on Snapchat - ...
In this grand opening episode of Sidewalk Cop, our villain leaves a little boy heart broken as he steals his favorite toy, a BB8. The police are quick to respond and are on his tail for what turns into an exhilarating roller coaster chase and finish that you won't want to miss. Please subscribe and watch our other exciting videos: Sidewalk Cop - Pirates of the Pacific https://youtu.be/IAbnlCecmxU and Sidewalk Cop - The Pirate Duel https://youtu.be/pLYTT2CHc-g Please subscribe and share this video with your friends and on social media. Without your support we can't make these fun videos. Thanks so much for watching our channel and supporting us. Music: Hitman by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) S...
Straight to the session baby " Music by Chillhop Records! https://www.youtube.com/user/Chillhopdotcom Artist: Birocratic: https://soundcloud.com/birocratic What an amazing day of skateboarding. I'm super stoked on the session, the beautiful views, the amazing friends I met, and get to spend time with. This trip emobies the life I've always dreamed of living (: Thanks dudes. TWITTER: https://twitter.com/johnhilltube FACEBOOK: https://www.facebook.com/johnhilltube SNAPCHAT: @john249hill INSTAGRAM: @john249hill For Fan Mail (not extravagant gifts): PO BOX 721632 Newport, KY 41072-1632
GTA 5 mods , GTA 5 PC Mods and GTA 5 Funny Moments are here! In this "GTA 5 Mods" showcase video with epic GTA 5 Mods gameplay with the GTA 5 Police Mod! We become cops and roam the streets! With GTA 5 funny moments and more! We make arrests, high speed chases and fight crime! The GTA 5 LSPDFR mod is an Amazing GTA 5 police mod with great features that make for an awesome GTA 5 Gameplay experience. Get GTA 5 For 80% off including Shark Cards! https://www.g2a.com/r/teg Previous GTA 5 Video: https://youtu.be/dMor7fGqBWs GTA 5 Funny Moments Playlist: https://www.youtube.com/playlist?list=PLZxNh0rxsJCY76G1HihWjXCcJFvsEShbz Also Check Out: Team Epiphany Next - https://www.youtube.com/c/teamepiphanynextgaming Follow The Stream Team! • HikePlays - https://www.youtube.com/user/HikePlays • Typ...
Kindergarten Cop movie clips: http://j.mp/15vWZPr BUY THE MOVIE: http://amzn.to/sxRJSr Don't miss the HOTTEST NEW TRAILERS: http://bit.ly/1u2y6pr CLIP DESCRIPTION: Kimble (Arnold Schwarzenegger) tracks down a witness at a party to help him identify his perp. FILM DESCRIPTION: Arnold Schwarzenegger sheds his action image in Ivan Reitman's police comedy Kindergarten Cop, where he plays an undercover cop teaching a class of hyperactive six-year-olds. As the film begins, John Kimble (Schwarzenegger) and his partner Phoebe O'Hara (Pamela Reed) are in pursuit of notorious drug dealer Cullen Crisp (Richard Tyson) and his scabrous mother Eleanor (Carroll Baker). John learns Cullen is searching for his ex-wife and his little boy, and Kimble plans to nail them when they find the former wife, who i...
NEW RP 2012 EPISODES ARE HERE!!! http://youtu.be/I63_Zw1lnso Special Edition DVD! http://bit.ly/hccMLv Thanks for supporting us!! Before you leave mean comments, just know that our friend Ponce (the Cop) is an awesome and talented young dude who loves performing and making light of his Down syndrome. He's a smart and funny guy, and has complete awareness of his actions and decisions. And we all had a great time shooting "Retarded Policeman!" DOES PONCE GET PAID FOR THIS!? YES!!! He's not only our friend, but also this is a real acting job for him. The more people who subscribe and watch, the more money he makes. (More subscribers = more views = more money for Ponce.) THANKS FOR SUBSCRIBING! Retarded Policeman: The Series series created by Greg Benson & Kim Evey ...
Beverly Hills Cop (USA - 1984). Opening credits and cigarette truck chase scene. Film directed by Martin Brest, with Eddie Murphy, Judge Reinhold, John Ashton, Lisa Eilbacher, Ronny Cox, Steven Berkoff. Soundtrack: 1. Glenn Frey - The Heat Is On / 2. The Pointer Sisters - Neutron Dance
A half hour of LSPDFR. I am going to make this into a series once I get commentary to work while I am playing. Enjoy!
Cop and 1/2: www.balisfreecinema.tarboss.com/udtlkd5
[Intro]
Loc'N
[Verse 1: Cap1]
Look, thick bad bitch she a red bone
Ride shotgun love to get head from
Told me tell her when its coming told her here it come
Then its murder in the sheets nigga red rum
Put her to sleep like a lulla bye
I aint you, Im the other guy
Got girls on girls thats the whole Aces
Got my money up now I need more haters
Big face Rollie with the stones in it
Drop top coupe gettin' dome in it
Pulled it off the lot told em chrome kit it
Bitches lookin' at a nigga like he gon' get it
Fly nigga no parachute
Pulled up like where the roof?
Looked at her like where the roo?
Body fit in that dress like bod-a-boom
[Bridge: Cap 1]
Roll something, smoke something get ratchet
Bust it open look back get ratchet
In the middle of the club with the ratchet
If a nigga really want it can happen
[Hook: Cap 1]
West coast niggas straight loc'n
East coast niggas straight loc'n
Midwest niggas straight loc'n
Got a section full of bitches they postin' (x3)
[Verse 2: Cap 1]
Black shades on Ray Charles
Givanchi with the grey sharks
Shootin' money on the bitches like an AR
Told her everything covered like State Farm
Pocket on swole like a fat nigga
Anything I spend I make it back nigga
Hit her once, fell asleep, now Im back in her
Make her run to the money like a track sprinter
Walkin' on Sunati these eight-fifty
Bitches say I'm brand new cause she cant get me
Room full of bad bitches nigga choose one
Two seater fit three had to lose some
[Bridge]
[Hook]
[Verse 3: Nipsey Hussle]
Hell yeah, ballin' is a habit ugh
Niggas like us gotta have it huh?
AR 15 automatic huh?
I ducked a bad bitch too dramatic
I got money days, hoes cant play me
See me out swingin' shit thug cant phase me
Owe me money? pay me
Fame cant change me
Black locs gold Rollie like I'm still gang bangin' oh
[Bridge]