Bless you, or God bless you, is a common English expression addressed to a person after they sneeze. The origin of the custom and its original purpose are unknown.

An alternative response to sneezing is the German word Gesundheit or Salud (meaning Health) in the Spanish language.

Several possible origins are commonly given. The practice of blessing someone who sneezes, dating as far back as at least AD 77, however, is far older than most specific explanations can account for.

One explanation holds that the custom originally began as an actual blessing. Gregory I became Pope in AD 590 as an outbreak of the bubonic plague was reaching Rome. In hopes of fighting off the disease, he ordered unending prayer and parades of chanters through the streets. At the time, sneezing was thought to be an early symptom of the plague. The blessing ("God bless you!") became a common effort to halt the disease.

A variant of the Pope Gregory I story places it with Pope Gregory VII, then tells the common story of "Ring Around the Rosey" being connected to the same plague.

John Winston Ono Lennon, MBE (9 October 1940 – 8 December 1980) was an English musician and singer-songwriter who rose to worldwide fame as one of the founder members of The Beatles, one of the most commercially successful and critically acclaimed acts in the history of popular music. Together with Paul McCartney, he formed one of the most celebrated songwriting partnerships of the 20th century.

Born and raised in Liverpool, Lennon became involved as a teenager in the skiffle craze; his first band, The Quarrymen, evolved into The Beatles in 1960. As the group disintegrated towards the end of the decade, Lennon embarked on a solo career that produced the critically acclaimed albums John Lennon/Plastic Ono Band and Imagine, and iconic songs such as "Give Peace a Chance" and "Imagine". After his marriage to Yoko Ono in 1969, he changed his name to John Ono Lennon. Lennon disengaged himself from the music business in 1975 to devote time to raising his infant son Sean, but re-emerged with Ono in 1980 with the new album Double Fantasy. He was murdered three weeks after its release.

Kanye Omari West ( /ˈkɑːnjeɪ/; born June 8, 1977) is an American musician, film director and fashion designer. West first rose to fame as a producer for Roc-A-Fella Records, where he eventually achieved recognition for his work on Jay-Z's album The Blueprint, as well as hit singles for musical artists including Alicia Keys, Ludacris, and Janet Jackson. His style of production originally used pitched-up vocal samples from soul songs incorporated with his own drums and instruments. However, subsequent productions saw him broadening his musical palette and expressing influences encompassing '70s R&B, baroque pop, trip hop, arena rock, folk, alternative, electronica, synthpop, and classical music.

West released his debut album The College Dropout in 2004, his second album Late Registration in 2005, his third album Graduation in 2007, his fourth album 808s & Heartbreak in 2008, and his fifth album My Beautiful Dark Twisted Fantasy in 2010. West released a collaborative album, Watch the Throne with Jay-Z in 2011, which is the duo's first collaborative album. His five solo albums, all of which have gone platinum, have received numerous awards and critical acclaim. As of 2012, West has won a total of eighteen Grammy Awards, making him one of the most awarded artists of all-time. All albums have been very commercially successful, with My Beautiful Dark Twisted Fantasy becoming his fourth consecutive No. 1 album in the U.S. upon release. West has had 5 songs exceed 3 million in digital sales as of July 2011, with "Gold Digger" selling 3,086,000, "Stronger" selling 4,402,000, "Heartless" selling 3,742,000, "E.T." selling over 4,000,000 and "Love Lockdown" selling over 3,000,000 placing him third in overall digital sales of the past decade. He has sold over 30 million digital songs in the United States making him one of the best-selling digital artists of all-time.