-
Drug discovery and development process
Discovering and bringing one new drug to the market typically takes an average of 14 years of research and clinical development efforts. Learn about the many different steps in the complex drug discovery and development process.
© 2011 Novartis AG
published: 14 Jan 2011
-
Drug Discovery Phases = Introduction to Drug Development (HINDI) By Solution Pharmacy
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv
Important Link-
Experimental Animals used in Pharmacology Laboratory- https://www.youtube.com/watch?v=kAxTb...
Hot Plate Method- https://www.youtube.com/watch?v=_j2DjN5k6nE
Tail Flick Method- https://www.youtube.com/watch?v=Ixa_XoaaYJI
Actophotometer- https://www.youtube.com/watch?v=h8XcbVdOw1s
Student organ Bath- Parts and Function- https://www.youtube.com/watch?v=LlM3OuwhjOE
Student organ bath- Setting technique- https://www.youtube.com/watch?v=PHQpkr8GVvI
Pharmacognosy 4th Semester Playlist- https://www.youtube.com/playlist?list...
Drug Interaction (Part01) - https://www.youtube.com...
published: 31 Mar 2019
-
How Does the FDA Approve a Drug?
Have you ever taken an over the counter medication for heartburn? How about an antibiotic for an ear infection? At some point pretty much all of us have visited a pharmacy to pick up a drug, but likely didn't consider where these drugs come from or how they are made.
Whether you're talking about something for seasonal allergies or your grandparent's arthritis medication, the act of bringing a drug to market is long and complex. I'm not an expert, but HCT intern Rachel Hoffman is, and with her help, that's the topic of this week's Healthcare Triage.
For those of you who want to read more, go here:
http://theincidentaleconomist.com/wordpress/?p=63822
John Green -- Executive Producer
Stan Muller -- Director, Producer
Aaron Carroll -- Writer
Mark Olsen -- Graphics
http://www.twitter.com...
published: 20 Jul 2015
-
How Do Drugs Get Their Names?
Who names drugs? Why all the funny names? A number of months ago, we did an episode on how a drug comes to market with the help of out HCT intern, pharmD student Rachel Hoffman. She also helped us out with our episode on Flibanserin.
We get a lot of questions from you about drugs. What's the difference between a generic and name brand drug? How do people feel about them? What's the difference with biologics? With her help, we're going to tackle those in the upcoming weeks.
Let's start at the beginning. What's in a name? That which we call a drug. By any other name would be so . . . effective? Brand name and generic drugs: are there any differences? Who regulates them? And what's with all the names anyway? That's the topic of today's HealthCare Triage.
Those of you who want to read mo...
published: 03 Nov 2015
-
What is PHARMACEUTICAL DRUG? What does PHARMACEUTICAL DRUG mean?
✪✪✪✪✪ http://www.theaudiopedia.com ✪✪✪✪✪
What is PHARMACEUTICAL DRUG? What does PHARMACEUTICAL DRUG mean?
A pharmaceutical drug (also referred to as a pharmaceutical, pharmaceutical preparation, pharmaceutical product, medicinal product, medicine, medication, medicament, or simply a drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management.
Drugs are classified in various ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter dru...
published: 11 Aug 2016
-
New Intrinsically Enteric Capsule Technology for Pharmaceutical Drug Development
Finding more efficient ways to target drug delivery to the small intestine and provide effective enteric protection for heat or acid-sensitive and/or gastric-irritating drugs are significant challenges for the pharmaceutical industry. Capsugel has combined polymer science and capsule engineering to develop a line of intrinsically enteric capsules that preclude the need for enteric coating.
Learn how this novel solution, recently distinguished by the CPHI “Excellence in Formulation Award”, can accelerate preclinical and clinical development for compounds requiring enteric protection and/or delayed release in the upper GI tract.
published: 20 Jan 2017
-
IPPCR 2016: Concepts in Pharmaceutical Development Project Management
IPPCR 2016: Concepts in Pharmaceutical Development Project Management
Air date: Monday, February 01, 2016, 5:00:00 PM
Category: IPPCR
Runtime: 00:48:04
Description: The Introduction to the Principles and Practice of Clinical Research (IPPCR) is a course to train participants on how to effectively conduct clinical research. The course focuses on the spectrum of clinical research and the research process by highlighting epidemiologic methods, study design, protocol preparation, patient monitoring, quality assurance, and Food and Drug Administration (FDA) issues.
For more information go to http://clinicalcenter.nih.gov/training/training/ippcr1.html
Author: Christopher D. Breder, M.D., Ph.D., FDA
Permanent link: http://videocast.nih.gov/launch.asp?19461
published: 04 Feb 2016
7:22
Drug discovery and development process
Discovering and bringing one new drug to the market typically takes an average of 14 years of research and clinical development efforts. Learn about the many d...
Discovering and bringing one new drug to the market typically takes an average of 14 years of research and clinical development efforts. Learn about the many different steps in the complex drug discovery and development process.
© 2011 Novartis AG
https://wn.com/Drug_Discovery_And_Development_Process
Discovering and bringing one new drug to the market typically takes an average of 14 years of research and clinical development efforts. Learn about the many different steps in the complex drug discovery and development process.
© 2011 Novartis AG
- published: 14 Jan 2011
- views: 488750
21:51
Drug Discovery Phases = Introduction to Drug Development (HINDI) By Solution Pharmacy
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.goo...
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv
Important Link-
Experimental Animals used in Pharmacology Laboratory- https://www.youtube.com/watch?v=kAxTb...
Hot Plate Method- https://www.youtube.com/watch?v=_j2DjN5k6nE
Tail Flick Method- https://www.youtube.com/watch?v=Ixa_XoaaYJI
Actophotometer- https://www.youtube.com/watch?v=h8XcbVdOw1s
Student organ Bath- Parts and Function- https://www.youtube.com/watch?v=LlM3OuwhjOE
Student organ bath- Setting technique- https://www.youtube.com/watch?v=PHQpkr8GVvI
Pharmacognosy 4th Semester Playlist- https://www.youtube.com/playlist?list...
Drug Interaction (Part01) - https://www.youtube.com/watch?v=Z_vON...
Drug Interaction Part- 02- https://www.youtube.com/watch?v=48CD2...
Free model question paper for pharmacology 01 (All units) –
https://drive.google.com/drive/folders/1d61HhxtPwkK3TqY2ZD45z_shGayyG3xO?usp=sharing
Free Pharmacology- 1 notes (made by students) –
https://drive.google.com/open?id=1PRaNYy7_a60FCIpDzKTIK4gxOLhBclFQ
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes pre-clinical research on microorganisms and animals, filing for regulatory statutes, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug.
(1) The first step in the drug development process involves discovery work. This is where drug development companies choose a molecule, such as a gene or protein, to target with a drug.
(2) The next step in the drug development process is preclinical testing, which in itself is divided into two subcomponents: in vitro and in vivo testing. In vitro testing examines the drug molecules' interactions in test tubes and within the lab setting.
(3) The third step involves submitting an Investigational New Drug Application to the FDA prior to beginning human clinical trials.
(4)Clinical trials
Phase I trials, usually in healthy volunteers, determine safety and dosing.
Phase II trials are used to get an initial reading of efficacy and further explore safety in small numbers of patients having the disease targeted by the NCE.
Phase III trials are large, pivotal trials to determine safety and efficacy in sufficiently large numbers of patients with the targeted disease. If safety and efficacy are adequately proved, clinical testing may stop at this step and the NCE advances to the new drug application (NDA) stage.
Phase IV trials are post-approval trials that are sometimes a condition attached by the FDA, also called post-market surveillance studies.
Get in touch with the solution by just clicking following links-
Facebook Page- https://www.facebook.com/pharmavideo/
Facebook Group- https://www.facebook.com/groups/solutionpharamcy
Instagram- https://www.instagram.com/solutionpharmacy/
Mail Us for Free Pharmacology Materials- solutionpharmacy@gmail.com
LinkedIn- http://linkedin.com/in/pushpendrakpatel
https://wn.com/Drug_Discovery_Phases_Introduction_To_Drug_Development_(Hindi)_By_Solution_Pharmacy
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv
Important Link-
Experimental Animals used in Pharmacology Laboratory- https://www.youtube.com/watch?v=kAxTb...
Hot Plate Method- https://www.youtube.com/watch?v=_j2DjN5k6nE
Tail Flick Method- https://www.youtube.com/watch?v=Ixa_XoaaYJI
Actophotometer- https://www.youtube.com/watch?v=h8XcbVdOw1s
Student organ Bath- Parts and Function- https://www.youtube.com/watch?v=LlM3OuwhjOE
Student organ bath- Setting technique- https://www.youtube.com/watch?v=PHQpkr8GVvI
Pharmacognosy 4th Semester Playlist- https://www.youtube.com/playlist?list...
Drug Interaction (Part01) - https://www.youtube.com/watch?v=Z_vON...
Drug Interaction Part- 02- https://www.youtube.com/watch?v=48CD2...
Free model question paper for pharmacology 01 (All units) –
https://drive.google.com/drive/folders/1d61HhxtPwkK3TqY2ZD45z_shGayyG3xO?usp=sharing
Free Pharmacology- 1 notes (made by students) –
https://drive.google.com/open?id=1PRaNYy7_a60FCIpDzKTIK4gxOLhBclFQ
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes pre-clinical research on microorganisms and animals, filing for regulatory statutes, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug.
(1) The first step in the drug development process involves discovery work. This is where drug development companies choose a molecule, such as a gene or protein, to target with a drug.
(2) The next step in the drug development process is preclinical testing, which in itself is divided into two subcomponents: in vitro and in vivo testing. In vitro testing examines the drug molecules' interactions in test tubes and within the lab setting.
(3) The third step involves submitting an Investigational New Drug Application to the FDA prior to beginning human clinical trials.
(4)Clinical trials
Phase I trials, usually in healthy volunteers, determine safety and dosing.
Phase II trials are used to get an initial reading of efficacy and further explore safety in small numbers of patients having the disease targeted by the NCE.
Phase III trials are large, pivotal trials to determine safety and efficacy in sufficiently large numbers of patients with the targeted disease. If safety and efficacy are adequately proved, clinical testing may stop at this step and the NCE advances to the new drug application (NDA) stage.
Phase IV trials are post-approval trials that are sometimes a condition attached by the FDA, also called post-market surveillance studies.
Get in touch with the solution by just clicking following links-
Facebook Page- https://www.facebook.com/pharmavideo/
Facebook Group- https://www.facebook.com/groups/solutionpharamcy
Instagram- https://www.instagram.com/solutionpharmacy/
Mail Us for Free Pharmacology Materials- solutionpharmacy@gmail.com
LinkedIn- http://linkedin.com/in/pushpendrakpatel
- published: 31 Mar 2019
- views: 92167
7:38
How Does the FDA Approve a Drug?
Have you ever taken an over the counter medication for heartburn? How about an antibiotic for an ear infection? At some point pretty much all of us have visited...
Have you ever taken an over the counter medication for heartburn? How about an antibiotic for an ear infection? At some point pretty much all of us have visited a pharmacy to pick up a drug, but likely didn't consider where these drugs come from or how they are made.
Whether you're talking about something for seasonal allergies or your grandparent's arthritis medication, the act of bringing a drug to market is long and complex. I'm not an expert, but HCT intern Rachel Hoffman is, and with her help, that's the topic of this week's Healthcare Triage.
For those of you who want to read more, go here:
http://theincidentaleconomist.com/wordpress/?p=63822
John Green -- Executive Producer
Stan Muller -- Director, Producer
Aaron Carroll -- Writer
Mark Olsen -- Graphics
http://www.twitter.com/aaronecarroll
http://www.twitter.com/crashcoursestan
http://www.twitter.com/johngreen
http://www.twitter.com/olsenvideo
And the housekeeping:
1) You can support Healthcare Triage on Patreon: http://vid.io/xqXr Every little bit helps make the show better!
2) Check out our Facebook page: http://goo.gl/LnOq5z
3) We still have merchandise available at http://www.hctmerch.com
https://wn.com/How_Does_The_Fda_Approve_A_Drug
Have you ever taken an over the counter medication for heartburn? How about an antibiotic for an ear infection? At some point pretty much all of us have visited a pharmacy to pick up a drug, but likely didn't consider where these drugs come from or how they are made.
Whether you're talking about something for seasonal allergies or your grandparent's arthritis medication, the act of bringing a drug to market is long and complex. I'm not an expert, but HCT intern Rachel Hoffman is, and with her help, that's the topic of this week's Healthcare Triage.
For those of you who want to read more, go here:
http://theincidentaleconomist.com/wordpress/?p=63822
John Green -- Executive Producer
Stan Muller -- Director, Producer
Aaron Carroll -- Writer
Mark Olsen -- Graphics
http://www.twitter.com/aaronecarroll
http://www.twitter.com/crashcoursestan
http://www.twitter.com/johngreen
http://www.twitter.com/olsenvideo
And the housekeeping:
1) You can support Healthcare Triage on Patreon: http://vid.io/xqXr Every little bit helps make the show better!
2) Check out our Facebook page: http://goo.gl/LnOq5z
3) We still have merchandise available at http://www.hctmerch.com
- published: 20 Jul 2015
- views: 162095
4:49
How Do Drugs Get Their Names?
Who names drugs? Why all the funny names? A number of months ago, we did an episode on how a drug comes to market with the help of out HCT intern, pharmD studen...
Who names drugs? Why all the funny names? A number of months ago, we did an episode on how a drug comes to market with the help of out HCT intern, pharmD student Rachel Hoffman. She also helped us out with our episode on Flibanserin.
We get a lot of questions from you about drugs. What's the difference between a generic and name brand drug? How do people feel about them? What's the difference with biologics? With her help, we're going to tackle those in the upcoming weeks.
Let's start at the beginning. What's in a name? That which we call a drug. By any other name would be so . . . effective? Brand name and generic drugs: are there any differences? Who regulates them? And what's with all the names anyway? That's the topic of today's HealthCare Triage.
Those of you who want to read more can go here: http://theincidentaleconomist.com/wordpress/?p=67626
John Green -- Executive Producer
Stan Muller -- Director, Producer
Aaron Carroll -- Writer
Mark Olsen -- Graphics
http://www.twitter.com/aaronecarroll
http://www.twitter.com/crashcoursestan
http://www.twitter.com/johngreen
http://www.twitter.com/olsenvideo
And the housekeeping:
1) You can support Healthcare Triage on Patreon: http://vid.io/xqXr Every little bit helps make the show better!
2) Check out our Facebook page: http://goo.gl/LnOq5z
3) We still have merchandise available at http://www.hctmerch.com
https://wn.com/How_Do_Drugs_Get_Their_Names
Who names drugs? Why all the funny names? A number of months ago, we did an episode on how a drug comes to market with the help of out HCT intern, pharmD student Rachel Hoffman. She also helped us out with our episode on Flibanserin.
We get a lot of questions from you about drugs. What's the difference between a generic and name brand drug? How do people feel about them? What's the difference with biologics? With her help, we're going to tackle those in the upcoming weeks.
Let's start at the beginning. What's in a name? That which we call a drug. By any other name would be so . . . effective? Brand name and generic drugs: are there any differences? Who regulates them? And what's with all the names anyway? That's the topic of today's HealthCare Triage.
Those of you who want to read more can go here: http://theincidentaleconomist.com/wordpress/?p=67626
John Green -- Executive Producer
Stan Muller -- Director, Producer
Aaron Carroll -- Writer
Mark Olsen -- Graphics
http://www.twitter.com/aaronecarroll
http://www.twitter.com/crashcoursestan
http://www.twitter.com/johngreen
http://www.twitter.com/olsenvideo
And the housekeeping:
1) You can support Healthcare Triage on Patreon: http://vid.io/xqXr Every little bit helps make the show better!
2) Check out our Facebook page: http://goo.gl/LnOq5z
3) We still have merchandise available at http://www.hctmerch.com
- published: 03 Nov 2015
- views: 76239
2:21
What is PHARMACEUTICAL DRUG? What does PHARMACEUTICAL DRUG mean?
✪✪✪✪✪ http://www.theaudiopedia.com ✪✪✪✪✪
What is PHARMACEUTICAL DRUG? What does PHARMACEUTICAL DRUG mean?
A pharmaceutical drug (also referred to as a pharmac...
✪✪✪✪✪ http://www.theaudiopedia.com ✪✪✪✪✪
What is PHARMACEUTICAL DRUG? What does PHARMACEUTICAL DRUG mean?
A pharmaceutical drug (also referred to as a pharmaceutical, pharmaceutical preparation, pharmaceutical product, medicinal product, medicine, medication, medicament, or simply a drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management.
Drugs are classified in various ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small-molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem-cell therapies). Other ways to classify medicines are by mode of action, route of administration, biological system affected, or therapeutic effects. An elaborate and widely used classification system is the Anatomical Therapeutic Chemical Classification System (ATC system). The World Health Organization keeps a list of essential medicines.
Drug discovery and drug development are complex and expensive endeavors undertaken by pharmaceutical companies, academic scientists, and governments. Governments generally regulate what drugs can be marketed, how drugs are marketed, and in some jurisdictions, drug pricing. Controversies have arisen over drug pricing and disposal of used drugs.
https://wn.com/What_Is_Pharmaceutical_Drug_What_Does_Pharmaceutical_Drug_Mean
✪✪✪✪✪ http://www.theaudiopedia.com ✪✪✪✪✪
What is PHARMACEUTICAL DRUG? What does PHARMACEUTICAL DRUG mean?
A pharmaceutical drug (also referred to as a pharmaceutical, pharmaceutical preparation, pharmaceutical product, medicinal product, medicine, medication, medicament, or simply a drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management.
Drugs are classified in various ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small-molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem-cell therapies). Other ways to classify medicines are by mode of action, route of administration, biological system affected, or therapeutic effects. An elaborate and widely used classification system is the Anatomical Therapeutic Chemical Classification System (ATC system). The World Health Organization keeps a list of essential medicines.
Drug discovery and drug development are complex and expensive endeavors undertaken by pharmaceutical companies, academic scientists, and governments. Governments generally regulate what drugs can be marketed, how drugs are marketed, and in some jurisdictions, drug pricing. Controversies have arisen over drug pricing and disposal of used drugs.
- published: 11 Aug 2016
- views: 3387
59:37
New Intrinsically Enteric Capsule Technology for Pharmaceutical Drug Development
Finding more efficient ways to target drug delivery to the small intestine and provide effective enteric protection for heat or acid-sensitive and/or gastric-ir...
Finding more efficient ways to target drug delivery to the small intestine and provide effective enteric protection for heat or acid-sensitive and/or gastric-irritating drugs are significant challenges for the pharmaceutical industry. Capsugel has combined polymer science and capsule engineering to develop a line of intrinsically enteric capsules that preclude the need for enteric coating.
Learn how this novel solution, recently distinguished by the CPHI “Excellence in Formulation Award”, can accelerate preclinical and clinical development for compounds requiring enteric protection and/or delayed release in the upper GI tract.
https://wn.com/New_Intrinsically_Enteric_Capsule_Technology_For_Pharmaceutical_Drug_Development
Finding more efficient ways to target drug delivery to the small intestine and provide effective enteric protection for heat or acid-sensitive and/or gastric-irritating drugs are significant challenges for the pharmaceutical industry. Capsugel has combined polymer science and capsule engineering to develop a line of intrinsically enteric capsules that preclude the need for enteric coating.
Learn how this novel solution, recently distinguished by the CPHI “Excellence in Formulation Award”, can accelerate preclinical and clinical development for compounds requiring enteric protection and/or delayed release in the upper GI tract.
- published: 20 Jan 2017
- views: 800
48:04
IPPCR 2016: Concepts in Pharmaceutical Development Project Management
IPPCR 2016: Concepts in Pharmaceutical Development Project Management
Air date: Monday, February 01, 2016, 5:00:00 PM
Category: IPPCR
Runtime: 00:48:04
...
IPPCR 2016: Concepts in Pharmaceutical Development Project Management
Air date: Monday, February 01, 2016, 5:00:00 PM
Category: IPPCR
Runtime: 00:48:04
Description: The Introduction to the Principles and Practice of Clinical Research (IPPCR) is a course to train participants on how to effectively conduct clinical research. The course focuses on the spectrum of clinical research and the research process by highlighting epidemiologic methods, study design, protocol preparation, patient monitoring, quality assurance, and Food and Drug Administration (FDA) issues.
For more information go to http://clinicalcenter.nih.gov/training/training/ippcr1.html
Author: Christopher D. Breder, M.D., Ph.D., FDA
Permanent link: http://videocast.nih.gov/launch.asp?19461
https://wn.com/Ippcr_2016_Concepts_In_Pharmaceutical_Development_Project_Management
IPPCR 2016: Concepts in Pharmaceutical Development Project Management
Air date: Monday, February 01, 2016, 5:00:00 PM
Category: IPPCR
Runtime: 00:48:04
Description: The Introduction to the Principles and Practice of Clinical Research (IPPCR) is a course to train participants on how to effectively conduct clinical research. The course focuses on the spectrum of clinical research and the research process by highlighting epidemiologic methods, study design, protocol preparation, patient monitoring, quality assurance, and Food and Drug Administration (FDA) issues.
For more information go to http://clinicalcenter.nih.gov/training/training/ippcr1.html
Author: Christopher D. Breder, M.D., Ph.D., FDA
Permanent link: http://videocast.nih.gov/launch.asp?19461
- published: 04 Feb 2016
- views: 15887