Business-to-business (B2B) describes commerce transactions between businesses, such as between a manufacturer and a wholesaler, or between a wholesaler and a retailer. Contrasting terms are business-to-consumer (B2C) and business-to-government (B2G).

The volume of B2B (Business-to-Business) transactions is much higher than the volume of B2C transactions. The primary reason for this is that in a typical supply chain there will be many B2B transactions involving sub components or raw materials, and only one B2C transaction, specifically sale of the finished product to the end customer. For example, an automobile manufacturer makes several B2B transactions such as buying tires, glass for windscreens, and rubber hoses for its vehicles. The final transaction, a finished vehicle sold to the consumer, is a single (B2C) transaction.

B2B is also used in the context of communication and collaboration. Many businesses are now using social media to connect with their consumers (B2C); however, they are now using similar tools within the business so employees can connect with one another. When communication is taking place amongst employees, this can be referred to as "B2B" communication.

Dwayne Michael Carter, Jr. (born September 27, 1982), better known by his stage name Lil Wayne, is an American rapper. At the age of nine, Lil Wayne joined Cash Money Records as the youngest member of the label, and half of the duo, The B.G.'z, with B.G.. In 1997, Lil Wayne joined the group Hot Boys, which also included rappers Juvenile, B.G., and Young Turk. Hot Boys debuted with Get It How U Live! that year. Lil Wayne gained most of his success with the group's major selling album Guerrilla Warfare, released in 1999. Also in 1999, Lil Wayne released his Platinum debut album Tha Block Is Hot, selling over one million copies in the U.S.

Although his next two albums Lights Out (2000) and 500 Degreez (2002) were not as successful (only reaching Gold status), Lil Wayne reached higher popularity in 2004 with Tha Carter, which included the single "Go D.J." Wayne also appeared on the Destiny's Child top ten single "Soldier" that year. In 2005, the sequel to Tha Carter, Tha Carter II, was released. In 2006 and 2007, Lil Wayne released several mixtapes and appeared on several popular rap and R&B singles. His most successful album, Tha Carter III, was released in 2008 and sold over 1 million copies in the U.S. its first week of release. It included the number-one single "Lollipop" featuring Static Major. It also includes the singles "A Milli" and "Got Money" featuring T-Pain and won the Grammy Award for Best Rap Album.