- published: 02 Dec 2012
- views: 182905
Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It works to raise the concentration of glucose in the bloodstream. Its effect is opposite that of insulin, which lowers the glucose.
The pancreas releases glucagon when the concentration of glucose in the bloodstream falls too low. Glucagon causes the liver to convert stored glycogen into glucose, which is released into the bloodstream. High blood-glucose levels stimulate the release of insulin. Insulin allows glucose to be taken up and used by insulin-dependent tissues. Thus, glucagon and insulin are part of a feedback system that keeps blood glucose levels at a stable level. Glucagon belongs to a family of several other related hormones.
It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.
Glucagon generally elevates the concentration of glucose in the blood by promoting gluconeogenesis and glycogenolysis.
Glucose is stored in the liver in the form of the polysaccharide glycogen, which is a glucan (a polymer made up of glucose molecules). Liver cells (hepatocytes) have glucagon receptors. When glucagon binds to the glucagon receptors, the liver cells convert the glycogen into individual glucose molecules and release them into the bloodstream, in a process known as glycogenolysis. As these stores become depleted, glucagon then encourages the liver and kidney to synthesize additional glucose by gluconeogenesis. Glucagon turns off glycolysis in the liver, causing glycolytic intermediates to be shuttled to gluconeogenesis.
Khan Academy is a non-profit educational organization created in 2006 by educator Salman Khan with the aim of providing a free, world-class education for anyone, anywhere. The organization produces short lectures in the form of YouTube videos. In addition to micro lectures, the organization's website features practice exercises and tools for educators. All resources are available for free to anyone around the world. The main language of the website is English, but the content is also available in other languages.
The founder of the organization, Salman Khan, was born in New Orleans, Louisiana, United States to immigrant parents from Bangladesh and India. After earning three degrees from the Massachusetts Institute of Technology (a BS in mathematics, a BS in electrical engineering and computer science, and an MEng in electrical engineering and computer science), he pursued an MBA from Harvard Business School.
In late 2004, Khan began tutoring his cousin Nadia who needed help with math using Yahoo!'s Doodle notepad.When other relatives and friends sought similar help, he decided that it would be more practical to distribute the tutorials on YouTube. The videos' popularity and the testimonials of appreciative students prompted Khan to quit his job in finance as a hedge fund analyst at Connective Capital Management in 2009, and focus on the tutorials (then released under the moniker "Khan Academy") full-time.
Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/chemical-processes/bioenergetics/v/tissue-specific-metabolism-and-the-metabolic-states?utm_source=YT&utm;_medium=Desc...
A short how to video guide about glucagen injections. Produced by the UCLH children and young people's diabetes service.
Mrs. Foy explains how the hormones insulin and glucagon keep blood glucose levels in homeostasis
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In this video, a certified diabetes educator from Mayo Clinic explains the equipment and process for using glucagon for people with diabetes.
See how insulin and glucagon control blood sugar levels
It needs me, and I need it. Translated by: Cysote The Japanese Lyrics and Translation can be found here: https://docs.google.com/document/d/1M9GJix3T7jq-l3RwnRurpahvk9BWloJI6xplpkiBPVY/edit?usp=sharing Original Nico Broadcast: http://www.nicovideo.jp/watch/sm27040863 Original TItle: グルカゴン Vocaloid: Megurine Luka Music and Video: EZFG mylist/18564543 Notes: This song was hard to understand, and so my translation is most likely inaccurate in places. (1) 0:49, 1:35, 2:36 The verb あげる (ageru) and conjugated verbs あがって (agatte) and あげられる (agarareru) were used without Kanji in the song. Due to this, there are a couple different things that each verb could mean such as rising, struggling, giving, suspension, indication, or apprehension. Since there are very little context clues to work ...