Luis Maria Alfageme (born 17 December 1984) is an Argentine footballer who plays for Casertana at Italian Lega Pro.
Alfageme was signed by then Serie A club Brescia in June 2003. In 2005–06 season he was loaned to Acireale then spent a brief spell at Serie B for Brescia. In January 2007 he returned to Serie C1 for Cremonese, then loaned to Pescara and in January 2008 left for Sambenedettese along with Pescara team-mate Gabriele Bartoletti and Axel Vicentini. In 2008–09 season, he left for Lanciano along with Vicentini.
In August 2009, he was signed by Serie B side Grosseto in co-ownership deal, for a peppercorn fee of €500. He played main as substitutes but also scored the winning goal for Grosseto in Coppa Italia and helped the club advanced to the third round.