Fenuki Tupou (born May 2, 1985) is an American football guard who is currently a member of the New Orleans Saints. He was drafted by the Philadelphia Eagles in the fifth round of the 2009 NFL Draft. He played college football at Oregon.

Tupou was raised in Antelope, California, where he attended Center High School as a two-way lineman. He went on to attend Sierra College for two years, earning a Junior College All-American honorable mention in 2005. Recruited by Oregon, he redshirted in 2006, before starting 23 games at offensive tackle for the Ducks over the course of his junior and senior year, earning All-Pacific-10 honors both seasons.

Tupou was drafted by the Philadelphia Eagles in the fifth round of the 2009 NFL Draft. He signed a 4-year contract with the team on June 6, 2009. He was placed on the injured reserve list on September 5, 2009. He was waived on September 4, 2010, and re-signed to the team's practice squad on September 13. His practice squad contract expired at the conclusion of the season, and was re-signed to a future contract on January 13, 2011.