NB: NO SLATE San Francisco, US, February 2, 2011 1. Christopher Voigt with Alvin Tamsir, graduate student in Biochemistry and Biophysics Department 2. Close shot petri dish with colonies of bacteria 3. Various University of California San Francisco, Mission Bay Campus 4. Christopher Voigt walking down corridor 5. SOUNDBITE: (English), Christopher Voigt, Associate Prof. & lead investigator, University of California San Francisco (UCSF) "What we're trying to do is to be able to program a living cell in the same way that you would program a robot or program a computer." 6. Close of petrie dish 7. Medium shot Christopher Voigt and colleague Alvin Tamsir 8. Close shot petri dish 9. SOUNDBITE (English), Christopher Voigt, Associate Prof. & lead investigator, University of California San Francisco (UCSF) "We're really focused in two major directions right now. One is to truly turn the programming language for life into something that looks very much like a programming language for a computer. Where somebody who is a genetic engineer can write code in the same way that an engineer at Google is programming one of their applications. We would be able to program a living cell." AP Television Boston, US, April 1, 2011 10. Wide of entrance to College of Engineering at Boston University 11. Close of sign for Biomedical Engineering Department at Boston University 12. Various scientist at work in laboratory 13. SOUNDBITE (English), James Collins, Professor of Biomedical Engineering, Boston University "So a cell is very much like a computer, in that it can take different inputs, perform logical operations on these inputs, and output some function. So for example it might be if A do B, if C do D. Like a computer, as a result of synthetic biology advances, a cell can also be reprogrammed, or programmed with novel functions. So that now instead of if A then B it could be if A then C, or if A then D." 14. Close shot of bottle 15. Various scientist at work 16. SOUNDBITE (English) James Collins, Professor of Biomedical Engineering, Boston University "This paper by Voigt and team is quite significant in that they now show that it's possible to program an entire population, taking advantage of the diversity of the population as opposed to programming just and individual cell. So much of the advances that have been made in synthetic biology over the last decade have focused on reprogramming an individual cell and seeing how it behaves. Voigt's team has shown you can engineer multiple cells and have them interact in a population to now create diverse and much more complicated functions." AP Television San Francisco, US, February 2, 2011 17. Mid shot of Tamsir working in laboratory 18. Close of dish being prepared with with bacteria 19. Close up of fluid in test tube 21. Close up of petri dishes being stacked on worktop in laboratory 22. Mid shot of Tamsir in at clean area of laboratory 23. Mid shot of dish containing cells engineered to produce fluorescent protein being placed under microscope 24. Close up of cells 25. Close of samples in rack 26. Various Tamsir loading tubes into centrifuge 27. SOUNDBITE: (English) Alvin Tamsir, graduate student in Biochemistry, Molecular Biology & Genetics, UCSF "It's surprising that you could actually start applying the principles in electrical engineering and computer science into biological systems and the more so we can do that, the more predictable biology will be and the more we can engineer biology to do interesting applications." 28. Close up pan of laboratory bench 29. Various of liquid being injected into equipment LEAD-IN: Scientists in California are hoping to revolutionise medicine with e-coli, a bacteria which is most famous for causing food poisoning. STORYLINE: You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/895d83524c3ae5290e5dec3c5d6d4809 Find out more about AP Archive: http://www.aparchive.com/HowWeWork

• published: 30 Jul 2015
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