Aksyon (lit. Action), whose weekday edition is also known as Aksyon Prime, is the flagship news program broadcast by TV5 in the Philippines. It is anchored by Cheryl Cosim and Erwin Tulfo, with special segments hosted by Shawn Yao and Lourd de Veyra on weekdays, while its weekend edition is anchored by Atty. Mike Templo, Maricel Halili, and Jove Francisco.

The program is broadcast Weeknights at 6:00 p.m. to 6:30 p.m. (PST), Saturdays and Sundays at 11:30 p.m. to 12:00 midnight (PST) except for some News5 special programs like News5 Debates and Dokyu5, airs on Sunday. The newscast is simulcasted on AksyonTV and on radio thru 92.3 News FM in Mega Manila.

The newscast is based on News5's slogan "Higit sa Balita, Impormasyon at Kaganapan, Aksyon" which literally means "Beyond the news, information, and events, Action." Aksyon premiered on April 5, 2010 at 9:00 pm with Paolo Bediones and Cheryl Cosim as its first anchors. The news program used a touch-screen television called "Aksyon Board." It is the first local newscast to report via Live-Pack in contrast to the OB Vans used by its competitors. There is also a round-up news update called Aksyon Ngayon anchored by Dindo Flora, Cristina Lazo, and former Tambayan 101.9 DJ Reggie Valdez.