Mosel is one of 13 German wine regions (Weinbaugebiete) for quality wines (QbA and Prädikatswein), and takes its name from the Moselle River (German: Mosel). Before 1 August 2007 the region was called Mosel-Saar-Ruwer, but changed to a name that was considered more consumer-friendly. The wine region is Germany's third largest in terms of production but is the leading region in terms of international prestige. The region covers the valleys of the rivers Moselle, Saar, and Ruwer near Koblenz and Trier in the federal state of Rhineland-Palatinate. The area is known for the steep slopes of the region's vineyards overlooking the river. At 65° degrees incline, the steepest recorded vineyard in the world is the Calmont vineyard located on the Mosel and belonging to the village of Bremm, and therefore referred to as Bremmer Calmont. The Mosel is mainly famous for its wines made from the Riesling grape, but Elbling and Müller-Thurgau also contributes to the production. Because of the northerly location of Mosel, the Riesling wines are often light, low in alcohol, crisp and high in acidity, and often exhibit "flowery" rather than "fruity" aromas.

Ernst Loosen is a German winemaker and owner of the wine producer Weingut Dr. Loosen, located just outside Bernkastel in the Mosel wine region. With over 70,000 annual bottle production, he is one of the larger producers in the Mosel region. He is particularly known for the quality of his Rieslings, having won "Riesling of the Year" in 1989 as awarded by the German wine trade magazine Feinschmecker.

In 2001, Gault-Millau named Ernst Loosen as the German winemaker of the year, and in 2005, Ernst Loosen was selected as Decanter's "Man of the Year". Weingut Dr.Loosen was awarded three stars in Eichelmann Deutschlands Weine 2009.