The Plymouth Brethren is a conservative, Evangelical Christian movement, whose history can be traced to Dublin, Ireland, in the late 1820s. Although the group is notable for not taking any official "church name" to itself, and not having an official clergy or liturgy, the title "The Brethren," is one that many of their number are comfortable with in that the Bible designates all believers as "brethren" (meaning "brothers"). "Brethren assemblies" are commonly perceived as being divided into at least two branches, the "Open Brethren" and the "Exclusive Brethren".

The Plymouth Brethren movement began in Dublin around 1827, and soon spread from Ireland to Britain. The first English assembly was in Plymouth, where the movement became well known. Brethren assemblies diffused throughout Europe and beyond.Leonard Strong led the formation about 1836 of assemblies in British Guiana among the slaves. In the early years, those involved were largely unknown to one another, with no direct contact between the various groups.

Plymouth ⁱ/ˈplɪməθ/ is a city and unitary authority area on the south coast of Devon, England, about 190 miles (310 km) south-west of London. It is situated between the mouths of the rivers Plym to the east and Tamar to the west, where they join Plymouth Sound. Since 1967, the City of Plymouth has included the suburbs of Plympton and Plymstock, which are on the east side of the River Plym.

Plymouth's history goes back to the Bronze Age, when its first settlement grew at Mount Batten. This settlement continued to grow as a trading post for the Roman Empire, until the more prosperous village of Sutton, the current Plymouth, surpassed it. In 1620, the Pilgrim Fathers left Plymouth for the New World and established Plymouth Colony – the second English settlement in what is now the United States of America. During the English Civil War the town was held by the Parliamentarians and was besieged between 1642 and 1646.

Throughout the Industrial Revolution, Plymouth grew as a major commercial shipping port, handling imports and passengers from the Americas, while the neighbouring town of Devonport grew as an important Royal Naval shipbuilding and dockyard town. In 1914 the three neighbouring and independent towns, viz., the county borough of Plymouth, the county borough of Devonport, and the urban district of East Stonehouse were merged to form a single County Borough. The new, merged town took the name of Plymouth which, in 1928, achieved city status. The city's naval importance later led to its targeting and partial destruction during World War II, an act known as the Plymouth Blitz. After the war the city centre was completely rebuilt.