Opone was an ancient city situated in the Horn of Africa. It is primarily known for its trade with the Ancient Egyptians, Romans, Greeks, Persia and the states of ancient India. Through archaeological remains, the ancient port city has been identified with the northeastern Hafun peninsula in modern-day Somalia.

Pottery found in Oponean tombs date back to the Mycenaean Kingdom of Greece that flourished between the 16th and 11th century BC. Its major periods of activity were during the 1st century BC and the 3rd to the 5th centuries AD. Opone was mentioned by an anonymous Greek merchant in the 1st century CE in his Periplus of the Erythraean Sea. The town is featured in the ancient document's thirteenth entry, which in part states:

Opone served as a port of call for merchants from Phoenicia, Egypt, Greece, Persia, Yemen, Nabataea, Azania, the Roman Empire and elsewhere,^{[citation needed]} as it sat at a strategic location along the coastal route from the Mochan trading center of Azania to the Red Sea. Merchants from as far afield as Indonesia and Malaysia passed through the city, exchanging spices, silks and other goods, before departing south for Azania or north to Yemen or Egypt on the trade routes that spanned the length of the Indian Ocean's rim. As early as 50 CE, it was well known as a center for the cinnamon trade, along with the barter of cloves and other spices, ivory, exotic animal skins and incense.