Kwekwe District is a settlement in central Zimbabwe. It is found is the Midlands Province. Kwekwe is the capital of the district. The district is bordered by the district Zhombe to the north and Gweru to the south.

Coordinates: 18°45′S 29°30′E / 18.75°S 29.5°E / -18.75; 29.5

Kwekwe or Kwe Kwe ( /ˈkweɪkweɪ/ KWAY-kway), formerly spelt Que Que, is a city in central Zimbabwe. It is located in the centre of the country (Midlands province)—roughly equidistant from Harare to the northeast and Bulawayo to the southwest. Its population stood at 47,607 in 1982, 75,425 in 1992 and the preliminary result of the 2002 census suggests a current population of 88,000. It is a centre for steel and fertilizer production in the country.

Kwekwe and neighbouring Redcliff are the headquarters of Zimbabwe Iron and Steel Company (ZISCO), the country's largest steelworks. It also hosts the Zimbabwe Iron and Smelting Company, the largest ferrochrome producer, and one of the biggest power processing plants, ZESA-Munyati.kwekwe is Zimbabwe's richest city in terms of minerals

Kwekwe town was founded (spelt Que Que) in 1898 as a gold mining town, and hosts Zimbabwe's National Mining Museum. The town remains an industrial centre of the country. The name stems from the Zulu word "isikwekwe", which means "scurvy", "mange" or "scab". Popular belief states that Kwekwe is named after the croaking noise made by the nearby river's frogs.