Shionogi & Company, Limited (塩野義製薬株式会社, Shionogi Seiyaku Kabushiki gaisha^?, TYO: 4507, OSE: 4507) is a Japanese pharmaceutical company best known for developing Crestor. Medical supply and brand name also uses Shionogi ("シオノギ").

Shionogi has business roots that date back to 1878, and was incorporated in 1919. Among the medicines produced are for hyperlipidaemia, antibiotics, and cancer medicines.

In Japan it is particularly known as a producer of antimicrobial and antibiotics. Because of antibiotic resistance and slow growth of the antibiotic market, it has teamed up with US based Schering-Plough to become a sole marketing agent for its products in Japan.

Shionogi had supported the initial formation of Ranbaxy Pharmaceuticals, a generic manufacturer based in India.

Virginia G. Madsen (born September 11, 1961) is an American actress and documentary film producer. She came to fame during the 1980s, having appeared in several films aimed at a teenage audience. Two decades later, she had an Academy Award and Golden Globe-nominated role in the 2004 film Sideways.

Madsen was born in Chicago, Illinois, the daughter of Elaine (née Melson), an Emmy-winning poet, producer and playwright who often works for PBS, and Calvin Madsen, a fireman. Madsen's mother left a career in corporate business to pursue a writing career. Madsen's brother is actor Michael Madsen. Her paternal grandparents were Danish and her mother has Irish and distant Native American ancestry. Madsen is a graduate of New Trier High School in Winnetka, Illinois.

Her first effort as an actor was as her brother’s assistant in magic shows the two would concoct for their family. She later attended the Ted Liss Acting Studio in Chicago and Harand Camp Adult Theater Seminar in Elkhart Lake, Wisconsin. Of her experience with Liss, she said: "I had wanted to join his class since I was 12. It was well worth the wait because I don't think I could have got that sort of training anywhere else especially in the United States...I always wanted to make a real career out of acting."