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Nucleotides are molecules that, when joined, make up the individual structural units of the nucleic acids RNA and DNA. In addition, nucleotides participate in cellular signaling (cGMP and cAMP), and are incorporated into important cofactors of enzymatic reactions (coenzyme A, FAD, FMN, and NADP+).
Nucleotide derivatives such as the nucleoside triphosphates play central roles in metabolism, in which capacity they serve as sources of chemical energy (ATP and GTP).
A nucleotide is composed of a nucleobase (nitrogenous base), a five-carbon sugar (either ribose or 2-deoxyribose), and one phosphate group. Without the phosphate group, the nucleobase and sugar compose a nucleoside. A nucleotide can thus also be called a nucleoside monophosphate. The phosphate groups form bonds with either the 2, 3, or 5-carbon of the sugar, with the 5-carbon site most common. Cyclic nucleotides form when the phosphate group is bound to two of the sugar's hydroxyl groups. Nucleotides contain either a purine or a pyrimidine base. Ribonucleotides are nucleotides in which the sugar is ribose. Deoxyribonucleotides are nucleotides in which the sugar is deoxyribose.
This page contains text from Wikipedia, the Free Encyclopedia -
http://en.wikipedia.org/wiki/Nucleotide
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
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What is DNA?
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I created this video with the YouTube Video Editor (http://www.youtube.com/editor) -
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Hi there, this is just a basic vid. I hope this is helpfull. Please subscribe for more to come=) -
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For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html A sin... -
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This video provides a brief description of DNA nucleotide structure and the process by which they can be connected to form larger DNA molecules. -
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Topic- nucleotide excision repair to dicscus the mechanism of DNA repair process. For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html Question source - www.indiabix.com -
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- Adenine
- Adenosine
- Amide nitrogen
- Archaeogenetics
- Aspartate
- Aspartic acid
- Atoms
- Base pair
- Biochemistry
- Biology
- Biosynthetic
- C1
- Cell (biology)
- Chemical bonds
- Chromosome
- Classical genetics
- Coenzyme A
- Cyclic ADP-ribose
- Cyclic di-GMP
- Cyclic nucleotide
- Cytidine
- Cytidine diphosphate
- Cytoplasm
- Cytosine
- De novo synthesis
- Deoxyadenosine
- Deoxycytidine
- Deoxyguanosine
- Deoxyribonucleoside
- Deoxyribonucleotide
- Deoxyribonucleotides
- Deoxyribose
- Deoxyuridine
- Dihydroorotase
- Dihydroorotic acid
- DNA
- Ecological genetics
- Enzyme
- FAD
- Folic acid
- Formate
- Freebase (chemistry)
- Gene
- Genetic code
- Genetic diversity
- Genetic engineering
- Genetic monitoring
- Geneticist
- Genetics
- Genome
- Genomics
- Glutamine
- Glycine
- Guanine
- Guanosine
- Heredity
- Histidine
- History of genetics
- Hydroxyl
- Hypoxanthine
- Immunogenetics
- IMP synthesis
- In vitro
- In vivo
- IUPAC
- Medical genetics
- Metabolism
- Moiety (chemistry)
- Molecular evolution
- Molecular genetics
- Molecule
- NADP+
- Nucleic acid
- Nucleic acids
- Nucleobase
- Nucleoside
- Nucleotide
- Nucleotide salvage
- Organelle
- Orotate
- Phosphate
- Phosphoramidite
- Population genetics
- PPAT
- Protecting group
- PRPP
- PRPS1
- PubMed Identifier
- Purine
- Purine analogue
- Purine metabolism
- Purine nucleotides
- Pyrimidine
- Pyrimidine analogue
- Pyrophosphate
- Pyrophosphoryl
- R5P
- Reverse genetics
- Ribonucleoside
- Ribonucleotide
- Ribonucleotides
- Ribose
- Ribose C1
- RNA
- Template Alcohols
- Template AminoAcids
- Template Eicosanoids
- Template Fatty acids
- Template Genetics
- Template Glycosides
- Template Lipids
- Template Metabolism
- Thymidine
- Thymine
- Tryptophan
- Uracil
- Uric acid
- Uridine
- Uridine diphosphate
- Uridine triphosphate
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Paul Andersen describes the molecular structure of DNA. He describes the major parts of a nucleotide and explains how they are assembled into a nucleic acid.... -
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I created this video with the YouTube Video Editor (http://www.youtube.com/editor) -
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Hi there, this is just a basic vid. I hope this is helpfull. Please subscribe for more to come=) -
Single nucleotide polymorphism SNP
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For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html A sin... -
DNA nucleotides and dehydration synthesis
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This video provides a brief description of DNA nucleotide structure and the process by which they can be connected to form larger DNA molecules. -
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Topic- nucleotide excision repair to dicscus the mechanism of DNA repair process. For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html Question source - www.indiabix.com -
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In this video I have explained the difference between nucleotide and nucleoside. Also in the end I have shared a small trick that I utilize to remember which is nucleotide or nucleoside. SUBSCRIBE TO THE CHANNEL FOR NEW VIDEO EVERY FRIDAY!!! https://www.youtube.com/channel/UC4DEiJn9RR6WWgj_9MGhEUw Facebook: https://www.facebook.com/nowiknow13 Twitter: https://twitter.com/rupalgogia -
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- Order: Reorder
- Duration: 10:31
- Updated: 05 Sep 2014
- author: Bozeman Science
Paul Andersen describes the molecular structure of DNA. He describes the major parts of a nucleotide and explains how they are assembled into a nucleic acid....
http://wn.com/What_is_DNA?
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- published: 08 Dec 2011
- views: 250372
- author: Bozeman Science
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- Order: Reorder
- Duration: 2:03
- Updated: 10 Aug 2013
- author: KathrynVault
I created this video with the YouTube Video Editor (http://www.youtube.com/editor)
http://wn.com/Structure_of_a_Nucleotide_in_RNA_and_DNA
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- Duration: 8:00
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http://wn.com/Nucleic_Acids
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Purine and Pyrimidine Nucleotide Biosynthesis
- Order: Reorder
- Duration: 12:30
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Welcome to Moof University! My name is Mahfoud, and I recently graduated from UC Riverside. I've made these videos to help students with introductory biochem...
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- views: 7990
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Human Physiology : What Is a Nucleotide?
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http://wn.com/Human_Physiology_What_Is_a_Nucleotide?
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- views: 24885
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DNA Structure Nucleotide - Simple And Quick Learning - Genomics part 1
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- Duration: 2:28
- Updated: 05 May 2014
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Hi there, this is just a basic vid. I hope this is helpfull. Please subscribe for more to come=)
http://wn.com/DNA_Structure_Nucleotide_-_Simple_And_Quick_Learning_-_Genomics_part_1
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- Order: Reorder
- Duration: 5:12
- Updated: 02 Sep 2014
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For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html A sin...
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DNA nucleotides and dehydration synthesis
- Order: Reorder
- Duration: 0:54
- Updated: 09 Aug 2013
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This video provides a brief description of DNA nucleotide structure and the process by which they can be connected to form larger DNA molecules.
http://wn.com/DNA_nucleotides_and_dehydration_synthesis
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- published: 01 Mar 2011
- views: 5004
- author: Johnny Clore
Nucleotide excision repair
- Order: Reorder
- Duration: 12:14
- Updated: 25 Sep 2014
Topic- nucleotide excision repair to dicscus the mechanism of DNA repair process.
For more information, log on to-
http://shomusbiology.weebly.com/
Download the study materials here-
http://shomusbiology.weebly.com/bio-materials.html
Question source - www.indiabix.com
http://wn.com/Nucleotide_excision_repair
Topic- nucleotide excision repair to dicscus the mechanism of DNA repair process.
For more information, log on to-
http://shomusbiology.weebly.com/
Download the study materials here-
http://shomusbiology.weebly.com/bio-materials.html
Question source - www.indiabix.com
- published: 25 Sep 2014
- views: 10
Nucleotide Excision Repair
- Order: Reorder
- Duration: 2:16
- Updated: 21 Nov 2013
Nucleotide Excision Repair
http://wn.com/Nucleotide_Excision_Repair
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- published: 21 Nov 2013
- views: 52
Nucleotide biosynthesis
- Order: Reorder
- Duration: 12:54
- Updated: 11 Sep 2014
Find more videos and resources at:
http://freebiologyschool.blogspot.com/p/medical-school.html
- Breakdown of Purines produces Uric acid (a nitrogenous waste)
- High levels of Uric acid can cause Gout
- Uric Acid levels are increased when:
1. Cell turnover is high (some kinds of cancer)
2. Glucose is being overly-shunted into the Pentose Phosphate Shunt
The nomenclature of Nucleotides changes depending on whether a sugar is attached and if a phosphate is attached.
Two pathways for biosynthesis:
De-Novo (From scratch) – Used in growth
Salvage pathway (Recycling) – Used to maintain
THF is used for nucleotide synthesis by acting as a carbon carrier
Ribose-5-Phosphate from Pentose Phosphate shunt is converted to PRPP, which is converted to phosphoribosylamine
Phosphoribosylamine is converted to IMP
IMP can go down two pathways, making either ATP or GTP
Pyrimidines are formed from Aspartate and Carbomoyl phosphate (same as urea cycle)
- Then PRPP is added (after the fact)
Carbomoyl Phosphate and Aspartate combine to form the Pyrimidine ring
- The pyrimidine ring is added to PRPP to form Orotidylate,
- UMP, UTP are formed from Orotidylate
- CTP is formed from UTP
http://wn.com/Nucleotide_biosynthesis
Find more videos and resources at:
http://freebiologyschool.blogspot.com/p/medical-school.html
- Breakdown of Purines produces Uric acid (a nitrogenous waste)
- High levels of Uric acid can cause Gout
- Uric Acid levels are increased when:
1. Cell turnover is high (some kinds of cancer)
2. Glucose is being overly-shunted into the Pentose Phosphate Shunt
The nomenclature of Nucleotides changes depending on whether a sugar is attached and if a phosphate is attached.
Two pathways for biosynthesis:
De-Novo (From scratch) – Used in growth
Salvage pathway (Recycling) – Used to maintain
THF is used for nucleotide synthesis by acting as a carbon carrier
Ribose-5-Phosphate from Pentose Phosphate shunt is converted to PRPP, which is converted to phosphoribosylamine
Phosphoribosylamine is converted to IMP
IMP can go down two pathways, making either ATP or GTP
Pyrimidines are formed from Aspartate and Carbomoyl phosphate (same as urea cycle)
- Then PRPP is added (after the fact)
Carbomoyl Phosphate and Aspartate combine to form the Pyrimidine ring
- The pyrimidine ring is added to PRPP to form Orotidylate,
- UMP, UTP are formed from Orotidylate
- CTP is formed from UTP
- published: 11 Sep 2014
- views: 8
Chapter 12A Part 2 - Nucleotide Structure
This episode explores in more detail the structure of DNA nucleotides. You will learn the different nitrogenous bases found in DNA and how they pair up using...
http://wn.com/Chapter_12A_Part_2_-_Nucleotide_Structure
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- views: 1575
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![Nucleotide excision repair [HD Animation]](http://web.archive.org./web/20150705100017im_/http://i1.ytimg.com/vi/rYreAcn04-M/0.jpg "Nucleotide excision repair [HD Animation]")
Nucleotide excision repair [HD Animation]
- Order: Reorder
- Duration: 2:12
- Updated: 05 Mar 2014
See an organised list of all the animations: http://doctorprodigious.wordpress.com/hd-animations/
http://wn.com/Nucleotide_excision_repair_HD_Animation_
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- published: 05 Mar 2014
- views: 8
#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
- Order: Reorder
- Duration: 49:34
- Updated: 06 Sep 2014
- author: Kevin Ahern
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate...
http://wn.com/_39_Biochemistry_Nucleotide_Metabolism_I_Lecture_for_Kevin_Ahern's_BB_451_551
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate...
- published: 10 Feb 2012
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- Order: Reorder
- Duration: 4:25
- Updated: 06 Dec 2014
In this video I have explained the difference between nucleotide and nucleoside. Also in the end I have shared a small trick that I utilize to remember which is nucleotide or nucleoside.
SUBSCRIBE TO THE CHANNEL FOR NEW VIDEO EVERY FRIDAY!!!
https://www.youtube.com/channel/UC4DEiJn9RR6WWgj_9MGhEUw
Facebook: https://www.facebook.com/nowiknow13
Twitter: https://twitter.com/rupalgogia
http://wn.com/Nucleotide_&_Nucleoside_-_What_is_the_difference!!!
In this video I have explained the difference between nucleotide and nucleoside. Also in the end I have shared a small trick that I utilize to remember which is nucleotide or nucleoside.
SUBSCRIBE TO THE CHANNEL FOR NEW VIDEO EVERY FRIDAY!!!
https://www.youtube.com/channel/UC4DEiJn9RR6WWgj_9MGhEUw
Facebook: https://www.facebook.com/nowiknow13
Twitter: https://twitter.com/rupalgogia
- published: 06 Dec 2014
- views: 3
DNA Repair III - Nucleotide Excision Repair
- Order: Reorder
- Duration: 15:15
- Updated: 17 Feb 2014
This video is about DNA Repair III - Nucleotide Excision Repair
http://wn.com/DNA_Repair_III_-_Nucleotide_Excision_Repair
This video is about DNA Repair III - Nucleotide Excision Repair
- published: 17 Feb 2014
- views: 8
DNA repair - global genome Nucleotide excision repair v 3.0 - Full HD
- Order: Reorder
- Duration: 0:28
- Updated: 02 Sep 2014
- author: Pedro Mendez
Nucleotide excision repair (NER), is a cellular DNA damage response induced by carcinogens such as: polycyclic aromatic hydrocarbons presents in tobacco (Ben...
http://wn.com/DNA_repair_-_global_genome_Nucleotide_excision_repair_v_3.0_-_Full_HD
Nucleotide excision repair (NER), is a cellular DNA damage response induced by carcinogens such as: polycyclic aromatic hydrocarbons presents in tobacco (Ben...
- published: 27 Oct 2010
- views: 33773
- author: Pedro Mendez
Nucleotide BLAST
- Order: Reorder
- Duration: 3:30
- Updated: 23 Jul 2012
- author: UTMBLibrary
Search nucleotide databases using a nucleotide query.
http://wn.com/Nucleotide_BLAST
Search nucleotide databases using a nucleotide query.
- published: 23 Jul 2012
- views: 943
- author: UTMBLibrary
BLAST - Nucleotide
http://www.abnova.com ) - The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotid...
http://wn.com/BLAST_-_Nucleotide
http://www.abnova.com ) - The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotid...
- published: 14 Jun 2010
- views: 4473
- author: Abnova
Nucleotide Drawing IB biology
- Order: Reorder
- Duration: 9:05
- Updated: 21 Sep 2013
Drawing DNA and RNA nucleotides. FYI: I accidently called P phosphate, but P is actually phosphorus. Remember PO4-- is phosphate!
http://wn.com/Nucleotide_Drawing_IB_biology
Drawing DNA and RNA nucleotides. FYI: I accidently called P phosphate, but P is actually phosphorus. Remember PO4-- is phosphate!
- published: 21 Sep 2013
- views: 56
Nucleotide Degradation
- Order: Reorder
- Duration: 6:33
- Updated: 11 Sep 2014
Made with Explain Everything
http://wn.com/Nucleotide_Degradation
Made with Explain Everything
- published: 11 Sep 2014
- views: 5
Genetics 101 (Part 2 of 5): What are SNPs?
- Order: Reorder
- Duration: 2:01
- Updated: 18 Apr 2012
In this video collaboration from Khan Academy and 23andMe, you'll learn about the variations in human DNA called SNPs, and how they can be used to understand relationships between people.
http://wn.com/Genetics_101_(Part_2_of_5)_What_are_SNPs?
In this video collaboration from Khan Academy and 23andMe, you'll learn about the variations in human DNA called SNPs, and how they can be used to understand relationships between people.
- published: 18 Apr 2012
- views: 236339
- Playlist
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10:31
What is DNA?
Paul Andersen describes the molecular structure of DNA. He describes the major parts of a ...
published: 08 Dec 2011
author: Bozeman Science
What is DNA?
What is DNA?
Paul Andersen describes the molecular structure of DNA. He describes the major parts of a nucleotide and explains how they are assembled into a nucleic acid....- published: 08 Dec 2011
- views: 250372
- author: Bozeman Science
2:03
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I created this video with the YouTube Video Editor (http://www.youtube.com/editor)...
published: 29 Oct 2011
author: KathrynVault
Structure of a Nucleotide in RNA and DNA
Structure of a Nucleotide in RNA and DNA
I created this video with the YouTube Video Editor (http://www.youtube.com/editor)- published: 29 Oct 2011
- views: 4322
- author: KathrynVault
8:00
Nucleic Acids
Paul Andersen explains the importance and structure of nucleic acids. He begins with an in...
published: 13 Nov 2012
author: Bozeman Science
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Paul Andersen explains the importance and structure of nucleic acids. He begins with an introduction to DNA and RNA. He then describes the important parts of...- published: 13 Nov 2012
- views: 92420
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12:30
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published: 30 Nov 2013
author: Moof University
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Welcome to Moof University! My name is Mahfoud, and I recently graduated from UC Riverside. I've made these videos to help students with introductory biochem...- published: 30 Nov 2013
- views: 7990
- author: Moof University
1:31
Human Physiology : What Is a Nucleotide?
Nucleotides are little components that make up DNA, and they are connected by phosphate mo...
published: 12 Nov 2008
author: eHow
Human Physiology : What Is a Nucleotide?
Human Physiology : What Is a Nucleotide?
Nucleotides are little components that make up DNA, and they are connected by phosphate molecules. Learn about the components of nucleotides, which includes ...- published: 12 Nov 2008
- views: 24885
- author: eHow
2:28
DNA Structure Nucleotide - Simple And Quick Learning - Genomics part 1
Hi there, this is just a basic vid. I hope this is helpfull. Please subscribe for more to ...
published: 21 Oct 2013
author: MrSimpleScience
DNA Structure Nucleotide - Simple And Quick Learning - Genomics part 1
DNA Structure Nucleotide - Simple And Quick Learning - Genomics part 1
Hi there, this is just a basic vid. I hope this is helpfull. Please subscribe for more to come=)- published: 21 Oct 2013
- views: 439
- author: MrSimpleScience
5:12
Single nucleotide polymorphism SNP
For more information, log on to- http://shomusbiology.weebly.com/ Download the study mater...
published: 04 Nov 2013
author: Suman Bhattacharjee
Single nucleotide polymorphism SNP
Single nucleotide polymorphism SNP
For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html A sin...- published: 04 Nov 2013
- views: 6055
- author: Suman Bhattacharjee
0:54
DNA nucleotides and dehydration synthesis
This video provides a brief description of DNA nucleotide structure and the process by whi...
published: 01 Mar 2011
author: Johnny Clore
DNA nucleotides and dehydration synthesis
DNA nucleotides and dehydration synthesis
This video provides a brief description of DNA nucleotide structure and the process by which they can be connected to form larger DNA molecules.- published: 01 Mar 2011
- views: 5004
- author: Johnny Clore
12:14
Nucleotide excision repair
Topic- nucleotide excision repair to dicscus the mechanism of DNA repair process.
For more...
published: 25 Sep 2014
Nucleotide excision repair
Nucleotide excision repair
Topic- nucleotide excision repair to dicscus the mechanism of DNA repair process. For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html Question source - www.indiabix.com- published: 25 Sep 2014
- views: 10
12:54
Nucleotide biosynthesis
Find more videos and resources at:
http://freebiologyschool.blogspot.com/p/medical-school....
published: 11 Sep 2014
Nucleotide biosynthesis
Nucleotide biosynthesis
Find more videos and resources at: http://freebiologyschool.blogspot.com/p/medical-school.html - Breakdown of Purines produces Uric acid (a nitrogenous waste) - High levels of Uric acid can cause Gout - Uric Acid levels are increased when: 1. Cell turnover is high (some kinds of cancer) 2. Glucose is being overly-shunted into the Pentose Phosphate Shunt The nomenclature of Nucleotides changes depending on whether a sugar is attached and if a phosphate is attached. Two pathways for biosynthesis: De-Novo (From scratch) – Used in growth Salvage pathway (Recycling) – Used to maintain THF is used for nucleotide synthesis by acting as a carbon carrier Ribose-5-Phosphate from Pentose Phosphate shunt is converted to PRPP, which is converted to phosphoribosylamine Phosphoribosylamine is converted to IMP IMP can go down two pathways, making either ATP or GTP Pyrimidines are formed from Aspartate and Carbomoyl phosphate (same as urea cycle) - Then PRPP is added (after the fact) Carbomoyl Phosphate and Aspartate combine to form the Pyrimidine ring - The pyrimidine ring is added to PRPP to form Orotidylate, - UMP, UTP are formed from Orotidylate - CTP is formed from UTP- published: 11 Sep 2014
- views: 8
8:33
Chapter 12A Part 2 - Nucleotide Structure
This episode explores in more detail the structure of DNA nucleotides. You will learn the ...
published: 20 Sep 2012
author: MrDBioCFC
Chapter 12A Part 2 - Nucleotide Structure
Chapter 12A Part 2 - Nucleotide Structure
This episode explores in more detail the structure of DNA nucleotides. You will learn the different nitrogenous bases found in DNA and how they pair up using...- published: 20 Sep 2012
- views: 1575
- author: MrDBioCFC
2:12
Nucleotide excision repair [HD Animation]
See an organised list of all the animations: http://doctorprodigious.wordpress.com/hd-anim...
published: 05 Mar 2014
Nucleotide excision repair [HD Animation]
Nucleotide excision repair [HD Animation]
See an organised list of all the animations: http://doctorprodigious.wordpress.com/hd-animations/- published: 05 Mar 2014
- views: 8
photo: AP / Fernando Vergara
04 Jul 2015
Now even royalty, of a sort, is turning on Donald Trump. Two weeks into to the ugly ruckus that began when he described Mexican immigrants as drug dealers and rapists while announcing his run for president, Paulina Vega, the reigning Miss Universe, has condemned his comments as “unjust and hurtful”. The fallout from his comments had already begun to seriously damage his business interests ... Donald Trump in quotes ... They’re bringing crime ... ....
photo: AP / Eric Draper
03 Jul 2015
In what could come as a big boast to conspiracy theorists' allegation of aliens' existence, UK's Ministry of Defence (MoD) might release the country's top secret on Unidentified Flying Object (UFO) sightings in the next few months. ....
photo: AP / Ali Louati
05 Jul 2015
TUNIS. Tunisian President Beji Caid Essebsi declared a state of emergency on Saturday to give his government more powers following an Islamic militant attack on a beach hotel, where 38 foreign tourists, mostly Britons, were killed. Tunisia’s emergency law temporarily gives the government more executive flexibility, hands the army and police more authority, and restricts certain rights such as the right to public assembly ... Apple Store ... ....
photo: AP / Jossy Ola
04 Jul 2015
Early on Friday, the terrorist group dragged at least 11 men from homes in Miringa, a remote village in the Nigeria’s northeast Borno state, and executed them in the presence of villagers. According to AFP, the men had allegedly escaped forced conscription by the armed group. These men had fled from Gwargware, their home village in Yobe state to seek refuge in Miringa, another resident noted ... (AFP photo) ... RS/AS/MHB. ....
photo: AP
04 Jul 2015
The Syrian army backed by the Lebanese armed group Hezbollah launched an assult on the city of Zabadani, near Damascus, in a fresh push to seize the last rebel stronghold along Lebanon’s border. Syrian TV reported on Saturday that President Bashar al-Assad's troops closed in on the rebels "on several fronts" and had inflicted heavy casualties on the fighters ... It showed footage of plumes of smoke hanging over Zabadani ... Source ... ....
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Japan’s Ministry of Health, Labour and Welfare Approves Gilead’s Harvoni®, the First Once-Daily Single Tablet ...
Business Wire03 Jul 2015
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Japan’s Ministry of Health, Labour and Welfare Approves Gilead’s Harvoni®, the First Once-Daily Single Tablet Regimen for the Treatment of Genotype 1 Chronic Hepatitis C (Gilead Sciences Inc)
Public Technologies03 Jul 2015
(Source. Gilead Sciences Inc) Japan's Ministry of Health, Labour and Welfare Approves Gilead's Harvoni®, the First Once-Daily Single Tablet Regimen for the Treatment of Genotype 1 Chronic Hepatitis C ... FOSTER CITY, Calif.--(BUSINESS WIRE)--Jul ... Harvoni combines the NS5A inhibitor ledipasvir with the nucleotide analog polymerase inhibitor sofosbuvir, approved by the MHLW under the trade name Sovaldi® in March 2015 ... Warnings ... Warnings ... U.S....
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The Times of India
02 Jul 2015
VARANASI ... A patent has been filed for the chip and the work has been published in the prestigious journal, 'Nature Scientific Reports', on June 26 ... According to BHU spokesperson Rajesh Kumar Singh, it's a breakthrough in rice genetic research as the high density microarray chip with 50,051 SNP (single nucleotide polymorphism) has been developed exclusively for DNA fingerprinting and breeding applications in rice ... ....
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How the mammoth got its wool: Scientists find gene variants involved (Penn State - The Pennsylvania State University)
Public Technologies02 Jul 2015
(Source. Penn State - The Pennsylvania State University). Evolutionary change in a gene reconstructed in the lab from the extinct woolly mammoth likely was part of a suite of adaptations that allowed the mammoth to survive in harsh arctic environments, according to new research ... The research team found a total of approximately 33 million places in the genomes where the letters, known as nucleotides, varied among the three species....
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The Irish Times
02 Jul 2015
What if finding DNA was all the police needed to know what a suspect looked like? This could become reality ... If forensic investigators cannot find a match for DNA found at a crime scene, the DNA profile can end up sitting in a computer or in a frozen sample ... How do such tests work? They rely on SNPs (single nucleotide polymorphisms, or “snips”), places where there is variation at a single letter site in DNA between people ... ... ....
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The Hindu
01 Jul 2015
Why do different people have different coloured eyes like blue, black, or brown?, asks Akriti Singh from Jabalpur, Madhya Pradesh. Eye colour eyes is determined by the amount of melanin in the iris, density of proteins, and the frequency of the scattering of light by the turbid medium in the stroma of the iris ... Different single-nucleotide polymorphism within OCA2 are associated with blue and green eyes ... Dr. Sainudeen Pattazhy ... Keywords....
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Ultra-stable JILA Microscopy Technique Tracks Tiny Objects for Hours (NIST - National Institute of Standards and Technology)
Public Technologies01 Jul 2015
(Source. NIST - National Institute of Standards and Technology) ... The microscope is on the left. The sample is mounted on the black block on top of the silver stage. The lasers and optics are on the right. Credit. Burrus/NIST ... The technology was designed to track the machinery of biological cells, down to the tiniest bits of DNA, a single "base pair" of nucleotides among the 3 billion of these chemical units in human genes ... * R ... Vol....
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Gilead Submits New Drug Application to U.S. Food and Drug Administration for Single Tablet Regimen for HIV Containing Rilpivirine, Emtricitabine and Tenofovir Alafenamide (R/F/TAF) (Gilead Sciences Inc)
Public Technologies01 Jul 2015
(Source. Gilead Sciences Inc) Gilead Submits New Drug Application to U.S ... TAF is a novel, investigational nucleotide reverse transcriptase inhibitor (NRTI) that has demonstrated high antiviral efficacy at a dose less than one-tenth that of Gilead's Viread® (tenofovir disoproxil fumarate, TDF), as well as improved renal and bone laboratory parameters as compared to TDF in clinical trials in combination with other antiretroviral agents....
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Business Wire
30 Jun 2015
MVIR) today announces a new discovery project for a cancer indication, a liver targeted nucleotide prodrug for the treatment of hepatocellular carcinoma (HCC). The project is based on the company’s expertise in nucleoside and nucleotide science and is the first cancer project to emerge from its in-house discovery efforts in oncology that were announced in 2014. “Our HCC nucleotide project has made very rapid progress aft ....
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Medivir announces the first cancer project derived from its in-house nucleotide platform (Medivir AB)
Public Technologies30 Jun 2015
Medivir announces the first cancer project derived from its in-house nucleotide platform ... MVIR) today announces a new discovery project for a cancer indication, a liver targeted nucleotide prodrug for the treatment of hepatocellular carcinoma (HCC) ... "Our HCC nucleotide project has made very rapid progress after its initiation last year" said Richard Bethell, EVP Discovery Research....
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Enanta Pharmaceuticals Announces the Appointment of Nathalie Adda, M.D. as Chief Medical Officer (Enanta Pharmaceuticals Inc)
Public Technologies30 Jun 2015
(Source. Enanta Pharmaceuticals Inc). WATERTOWN, Mass.--(BUSINESS WIRE)--Jun. 30, 2015-- Enanta Pharmaceuticals, Inc ... "Nathalie is a welcome addition to our executive management team ... Luly, Ph.D., President and CEO. Dr ... Most recently, Dr ... These inhibitors include members of the direct acting antiviral (DAA)AbbVie), NS5A, and nucleotide polymerase - as well as a host-targeted antiviral (HTA) inhibitor class targeted against cyclophilin....
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CORRECTING and REPLACING Enanta Pharmaceuticals Announces the Appointment of Nathalie Adda, M.D. as Chief Medical Officer (Enanta Pharmaceuticals Inc)
Public Technologies30 Jun 2015
(Source. Enanta Pharmaceuticals Inc). WATERTOWN, Mass.--(BUSINESS WIRE)--Jun. 30, 2015-- Third paragraph, fourth sentence of release should read ... The corrected release reads. ... AS CHIEF MEDICAL OFFICER. Enanta Pharmaceuticals, Inc ... Dr ... Dr ... These inhibitors include members of the direct acting antiviral (DAA)AbbVie), NS5A, and nucleotide polymerase - as well as a host-targeted antiviral (HTA) inhibitor class targeted against cyclophilin ... Source....
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Mount Sinai Scientists Develop New Approach for More Accurate and Comprehensive Whole Genome Assembly, Variant Discovery and Interpretation (Mount Sinai Hospital)
Public Technologies30 Jun 2015
(Source. Mount Sinai Hospital) A new strategy for uncovering difficult-to-detect, complex forms of genomic variation associated with human disease. New York ... Conventional next-generation sequencing (NGS) techniques are able to accurately detect certain types of variation, such as single nucleotide variants and small insertions or deletions, but miss many large or complex forms of genomic variation that are associated with human disease....
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