Holguín (Spanish pronunciation: [olˈɣin]) is a municipality and city, the capital of the Cuban Province of Holguín. It also includes a tourist area, offering beach resorts in the outskirts of the region.

It was founded as San Isidoro de Holguín in 1545, and it is named after its founder Captain García Holguín, a Spanish military officer. Prior to 1976, Holguin was located in the province of Oriente.

There are several small city parks such as Parque Infantil, Parque San Jose, Parque San Isidoro, Parque Marti among others, most central the Calixto García in the downtown area. Close by one finds the galleries Centro Provincial de Arte and Bayado, a library, the club Casa de la Trova, the Martí cinema, the Theatre Eddy Suñol, the Province Museum La Periquera, a science museum, and a history museum. From the hill Loma de la Cruz, where a large crucifix is installed, which can be ascended by its 450 stairs, one can oversee the whole city.

Holguín has a baseball stadium. The Frank País International Airport (city code HOG) is connected to Havana and several other world destinations.

Guillermo Uribe Holguín (sometimes spelled Uribe-Holguín) (17 March 1880 – 26 June 1971) was a Colombian composer and violinist and one of the most important Colombian cultural figures of his generation. He composed prolifically in many genres and founded the National Symphony Orchestra of Colombia (previously the orchestra of the National Conservatory).

Uribe Holguín was born in Bogotá. His father was Guillermo Uribe and his mother Mercédes Holguín. While studying at the School of Engineering, he simultaneously studied violin with Ricardo Figueroa, and composition with Santos Cifuentes and Augusto Azzali, at the National Academy of Music. He became dissatisfied with his progress, and sought out a private teacher, Narciso Garay. He completed his engineering studies. In 1903 he visited New York and for the first time he heard professional orchestras and opera. It was there that he started his series of 300 trozos, based on folk melodies, written for various instruments. In 1905 he was appointed professor of violin and harmony at the Academia. There, in December 1905, he conducted his Victimae Paschali for solo voice, chorus and orchestra.