Yenisei (Russian: Енисе́й), also written as Yenisey, is the largest river system flowing to the Arctic Ocean. It is the central of the three great Siberian rivers that flow into the Arctic Ocean (the other two being the Ob River and the Lena River). Rising in Mongolia, it follows a northerly course to the Yenisei Gulf in the Kara Sea, draining a large part of central Siberia, the longest stream following the Yenisei-Angara-Selenga-Ider river system.

The upper reaches, subject to rapids and flooding, pass through sparsely populated areas. The middle section is controlled by a series of massive hydroelectric dams fuelling significant Russian primary industry. Partly built by gulag labor in Soviet times, industrial contamination remains a serious problem in an area hard to police. Moving on through sparsely-populated taiga, the Yenisei swells with numerous tributaries and finally reaches the Kara Sea in desolate tundra where it is icebound for more than half the year.

The maximum depth of the Yenisei River is 80 feet (24 m) and the average depth is 45 feet (14 m). The depth of river outflow is 106 feet (32 m) and inflow is 101 feet (31 m).