Central Italy (Italian: Italia centrale or just Centro) is one of the five official statistical regions of Italy used by the National Institute of Statistics (ISTAT), a first level NUTS region and a European Parliament constituency. Central Italy encompasses four of the country's 20 regions:

Italy ⁱ/ˈɪtəli/ (Italian: Italia [iˈtaːlja]), officially the Italian Republic or the Republic of Italy (Italian: Repubblica italiana), is a unitary parliamentary republic in south-central Europe. To the north, it borders France, Switzerland, Austria and Slovenia along the Alps. To the south, it consists of the entirety of the Italian Peninsula, Sicily, Sardinia–the two largest islands in the Mediterranean Sea–and many other smaller islands. The independent states of San Marino and the Vatican City are enclaves within Italy, while Campione d'Italia is an Italian exclave in Switzerland. The territory of Italy covers some 301,338 km² (116,347 sq mi) and is influenced by a temperate seasonal climate. With 60.6 million inhabitants, it is the fifth most populous country in Europe, and the 23rd most populous in the world.

Rome, the capital of Italy, was for centuries a political and religious centre of Western civilisation as the capital of the Roman Empire and site of the Holy See. After the decline of the Roman Empire, Italy endured numerous invasions by foreign peoples, from Germanic tribes such as the Lombards and Ostrogoths, to the Byzantines and later, the Normans, among others. Centuries later, Italy became the birthplace of Maritime republics and the Renaissance, an immensely fruitful intellectual movement that would prove to be integral in shaping the subsequent course of European thought.