Year 1560 (MDLX) was a leap year starting on Monday (link will display the full calendar) of the Julian calendar.

Felice Anerio (1560 – 26 or 27 September 1614) was an Italian composer of the late Renaissance and early Baroque eras, and a member of the Roman School of composers. He was the older brother of another important, and somewhat more progressive composer of the same period, Giovanni Francesco Anerio.

Anerio was born in Rome and lived his entire life there. He sang as a boy soprano at the Julian Chapel (the Cappella Giulia) from 1568 until 1577 (by which time he was an alto), and then he sang at another church until 1580. Around this time he began to compose, especially madrigals; this was one of the few periods in his life during which he wrote secular music. Likely he was influenced by Luca Marenzio, who was hugely popular at the time and who was in Rome at the same time Anerio began composing. By 1584 Anerio had been appointed maestro di cappella at the Collegio degli Inglesi; he also seems to have been the choirmaster at another society of Rome's leading musicians called the vertuosa Compagnia de i Musici di Roma. These positions must have given him considerable opportunity to exercise his compositional talents, for he had already written the music, songs, madrigals and choruses, for an Italian Passion play by this time. In 1594, he replaced Palestrina as the official composer to the papal choir, which was the most prominent position in Rome for a composer.

Lope de Aguirre (c. 1510 – 27 October 1561) was a Basque Spanish conquistador in South America. Nicknamed El Loco, 'the Madman', Aguirre is best known for his final expedition, down the Amazon river, in search of the mythical El Dorado. At the beginning he was a minor official of the expedition, but he mutinied and gained control of it, and then rebelled against and defied the Spanish monarch Philip II. By the end of the expedition, Aguirre was defeated and killed. From then on, he was considered a symbol of cruelty and treachery in colonial Spanish America, and has become an antihero in literature, cinema and other arts.

Aguirre was born circa 1510 in the Araotz Valley (a valley and hamlet belonging to Oñati), close to Arantzazu in the province of Gipuzkoa, northern Spain. He was the son of a nobleman, possibly from a family of court clerks. Aguirre was in his twenties and living in Seville when Hernando Pizarro returned from Peru and brought back the treasures of the Incas, inspiring Aguirre to follow in his footsteps.

Peter Philips (also Phillipps, Phillips, Pierre Philippe, Pietro Philippi, Petrus Philippus, c. 1560–1628) was an eminent English composer, organist, and Catholic priest exiled to Flanders. He was one of the greatest keyboard virtuosos of his time, and transcribed or arranged several Italian motets and madrigals by such as Lassus, Palestrina, and Giulio Caccini for his instruments. Some of his keyboard works are found in the Fitzwilliam Virginal Book. Philips also wrote many sacred choral works.

Philips was born in 1560 or 1561, possibly in Devonshire or London. From 1572 to 1578 he began his career as a boy chorister at St Paul's Cathedral in London, under the aegis of the Catholic master of choristers, Sebastian Westcott (d. 1582), who had also trained the young William Byrd some twenty years earlier. Philips must have had a close relationship with his master, as he lodged in his house up to the time of Westcote's death, and was a beneficiary of his will.

In this same year of 1582 Philips left England for good, like so many others for reasons of his Catholicism, and stayed briefly in Flanders before travelling to Rome where he entered the service of Alessandro Farnese (1520–1589), with whom he stayed for three years, and was also engaged as organist at the English Jesuit College. It was here that in February 1585 he met a fellow Catholic exile, Thomas, third Baron Paget (c.1544-1590). Philips entered Paget's service as a musician, and the two left Rome in March 1585, travelling over several years to Genoa, Madrid, Paris, Brussels and finally Antwerp, where Philips settled in 1590 and where Paget died the same year.

John Knox (c. 1514 – 24 November 1572) was a Scottish clergyman and a leader of the Protestant Reformation who brought reformation to the church in Scotland. He was educated at the University of St Andrews or possibly the University of Glasgow and was ordained to the Catholic priesthood in 1536. Influenced by early church reformers such as George Wishart, he joined the movement to reform the Scottish church. He was caught up in the ecclesiastical and political events that involved the murder of Cardinal Beaton in 1546 and the intervention of the regent of Scotland, Mary of Guise. He was taken prisoner by French forces the following year and exiled to England on his release in 1549.

While in exile, The Rev. John Knox was licensed to work in the Church of England, where he quickly rose in the ranks to serve King Edward VI of England as a royal chaplain. In this position, he exerted a reforming influence on the text of the Book of Common Prayer. In England he met and married his first wife, Marjorie. When Mary Tudor ascended the throne and re-established Roman Catholicism, Knox was forced to resign his position and leave the country.