Afgooye (Somali: Afgooye, Arabic: أفجويي‎) is a town in the Shabeellaha Hoose region of southern Somalia.

It is situated about 25 kilometres west of Mogadishu, the nation's capital. The Shabelle River passes through the middle of the town.

Afgooye was part of Italian Somaliland during the early part of the 20th century. The Italians occupied the town in 1908 and in the process abolished the local slave market.

In the 1980s, Afgooye was a common destination for investors from the Gulf states. The Emir of Kuwait also reportedly used to visit the town during the holy month of Ramadan.

After the outbreak of the civil war in 1991, parts of the town became a place of refuge for many of southern Somalia's internally displaced people.

Afgooye is inhabited by numerous Somali clans, as well as some ethnic minority groups. (Murasade) Digil and Mirifle (Rahanweyn) sub-clans, the Wacdaan Cismaan sub-clan of the Mudulood, and the Garre are especially well-represented.

Afgooye is a geodetic datum used in Somalia. Afgooye datum is based on the Krasovsky ellipsoid and the Greenwich prime meridian.