The Soyuz-TMA is a recent revision of the Soyuz spacecraft, superseded in 2010 by the Soyuz TMA-M. (T – транспортный – Transportnyi – meaning transport, M – модифицированный – Modifitsirovannyi – meaning modified, A – антропометрический, – Antropometricheskii meaning anthropometric). It is used by the Russian Federal Space Agency for human spaceflight. The spacecraft features several changes to accommodate requirements requested by NASA in order to service the International Space Station, including more latitude in the height and weight of the crew and improved parachute systems. It is also the first expendable vehicle to feature a "glass cockpit." Soyuz-TMA looks identical to the earlier Soyuz-TM spacecraft on the outside, but interior differences allow it to accommodate taller occupants with new adjustable crew couches.

A Soyuz spacecraft consists of three parts (from front to back):

The first two portions are habitable living space. By moving as much as possible into the orbital module, which does not have to be shielded or decelerated during atmospheric re-entry, the Soyuz three-part craft is both larger and lighter than the two-part Apollo spacecraft's command module. The Apollo command module had six cubic meters of living space and a mass of 5000 kg; the three-part Soyuz provided the same crew with nine cubic meters of living space, an airlock, and a service module for the mass of the Apollo capsule alone. This does not consider orbital module that could be used instead of LEM in Apollo.

TMA may refer to: