The Khumalo are an African clan that originated in northern KwaZulu, South Africa. The Khumalos are part of a group of Zulus and Ngunis known as the Mtungwa. Others include the Mabaso, located between the Ndwandwe and the Mthethwa^{[disambiguation needed ]}.

Until the rise of Zwide and the Ndwandwes, life was a simple affair and the Khumalos located at Mkhuze had the best that the land which would become Zululand had to offer: plenty of water, fertile soil and grazing ground. But the Khumalos in the early nineteenth century would have to lose their neutrality and choose a side, and this they postponed for as long as they could. To please the Ndwandwe, Matshobana – a Khumalo chief – married the daughter of the Ndwandwe chief Zwide and sired a son, Mzilikazi. The Ndwandwes are amaNguni aseMbo, though all spoke a very similar language (all Nguni languages are similar).

When Matshobana did not tell Zwide about patrolling Mthethwa amabutho (soldiers), Zwide had Matshobana killed, and the leadership of the Khumalo fell to Mzilikazi. Mzilikazi immediately did not trust his grandfather, Zwide, and took fifty warriors to join Shaka. Shaka was overjoyed because the Khumalos would be useful spies on Zwide and the Ndwandwes. After a few battles, Shaka gave Mzilikazi the extraordinary honour of being chief of the Khumalos and to remain semi-independent from the Zulu, if Zwide could be defeated.

Kelly Khumalo South African singer and actress. She has so far^[when?] released three albums: TKO, Itshitshi and Siyajabula. Khumalo is from Spruitview in the East Rand and had been singing in church all her life until realizing that there is a whole bigger world out there. She was named the Best Newcomer of 2005 in the Afro Pop music circuit, and Khumalo released her latest^[when?] album Siyajabula in June 2007.

Theophilus Doctorson "Doctor" Khumalo (born 26 June 1967 in Soweto) is a retired South African soccer player. He is best known for being a star midfielder for Kaizer Chiefs as well as the South African national team, Bafana Bafana.

Having started his career in professional soccer in 1984 with Swallows Reserves, Khumalo then went to Kaizer Chiefs, where he initially played for the junior team. His father, Eliakim "Pro" Khumalo, a renowned player of the 1970s and early 1980s, served as his mentor. Khumalo was promoted to the senior team the following year, when he started a game against Orlando Pirates.

Khumalo went on to become a star player for Kaizer Chiefs and did not play for any other South African soccer club, only leaving them for short overseas playing periods – he signed with FIFA agent Marcelo Houseman who took him to Argentina first Argentinian club Ferrocarril Oeste for six months in 1995 and in 1996 he played for the Columbus Crew of Major League Soccer.

The high-point of Khumalo's soccer career was the 1990s; he was part of the Kaizer Chiefs teams that won three South African league championship titles and five knockout trophies and was also voted South African Footballer of the Year in 1992. During his career at the club, he played in a total of 380 league and cup games, scoring 74 goals.

Sibongile Khumalo (b.24 September 1957) is a South African singer.

Sibongile Khumalo was born in Soweto and guided by her father, Khabi Mngoma, a professor of music, where she studied violin, singing, drama and dance. She has a Bachelor of Arts (BA) degree in music from the University of Zululand and BA Honors from University of the Witwatersrand. In 1993 Khumalo won the Standard Bank Young Artist Award at the Grahamstown Festival.

Khumalo was the first person to sing the title role of Princess Magogo in the first African opera Princess Magogo ka Dinuzulu.

Sibongile Khumalo has established herself as a jazz singer in South Africa. So far, she has released three jazz albums: Sibongile Khumalo Live at the Market Theatre, Immortal Secrets and Ancient Evenings.

In 2009, Khumalo was honoured by Rhodes University in Grahamstown, South Africa by being awarded a Doctor of Music honoris causa.

Moses Khumalo (30 January 1979, in Soweto – 4 September 2006) was a South African jazz saxophonist. He studied at Manu Technical College from 1994–1998 after graduating from community college. He started with the piano but switched to the saxophone in February, 1995.

He first performed publicly at the Grahamstown National Arts Festival in 1995, and gained attention in the jazz world as a member of Moses Taiwa Molelekwa's band. In the following years he played with Hugh Masekela, Sibongile Khumalo, and Paul Hanmer. Khumalo had been dubbed "one of South Africa's most promising young saxophonists."

Moses Khumalo died of an apparent suicide by hanging on 4 September 2006.