Zakī al-Arsūzī (in Arabic: زكي الأرسوزي; Latakia, June 1899 – Damascus, 2 July 1968) was a Syrian philosopher, philolog, sociologist, historian, and Arab nationalist. His ideas played a significant role in the development of Ba'athism and its political movement. He published several books during his lifetime, the most notable being The Genius of Arabic in its Tongue (1943).

Born into a middle class family in Latakia, Syria, al-Arsuzi studied at the Sorbonne, where he became interested in nationalism. In 1930, he returned to Syria, where he became a member of the League of National Action (LNA) in 1933. In 1938 he moved to Damascus because of his disillusionment with party work, and in 1939 left the LNA. In Damascus al-Arsuzi established, and headed, a group consisting of mostly secondary school pupils who would often discuss European history, nationalism and philosophy. Shortly after leaving the LNA al-Arsuzi established the Arab National Party, an Arab nationalist party with a "defined creed". It was not a success and, on his return to Syria in November 1940, after a brief stay in Baghdad, al-Arsuzi established a new party, the Arab Ba'ath; by 1944, however, most of its members had left and joined Michel Aflaq's and Salah al-Din al-Bitar's Arab Ba'ath Movement, which subscribed to a nearly identical doctrine.