Histone H2a

Thursday, 04 November 2021

Latest News for: histone h2a

Edit

How plants quickly adapt to shifting environmental conditions

Technology Org 02 Aug 2021

The researchers then took a closer look at the role of histones in this process, in particular the histone variant H2A.Z ... The scientists found that canopy shade led to the removal of the histone H2A.Z at growth-regulating genes through the DNA binding of PIF7, which in turn activated their expression.

Edit

Unraveling DNA packaging: How histones and DNA interact

Phys Dot Org 01 Jun 2021

The researchers looked at the interaction between DNA and a histone called H2A, one of the five main histones ... Goro Nishide et al, High-Speed Atomic Force Microscopy Reveals Spatiotemporal Dynamics of Histone Protein H2A Involution by DNA Inchworming, The Journal of Physical Chemistry Letters (2021).

Edit

Researchers reveal key information about how genes turn on and off

Technology Org 29 May 2021

A protein called H2A.Z plays an important role in regulating this packaging of genes in different ways ... “H2A.Z is a type of protein called a histone variant,” said Lauren Cole, a former FSU doctoral student and the first author on the paper. “Because histone variants play an ...

Edit

Lockdown for genome parasites

Phys Dot Org 08 Apr 2021

They show that DDM1 targets TEs by binding H2A.W, a variant of the histone H2A, one of the building blocks that coat DNA to form the condensed and tightly packed heterochromatin ... The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W, Nature Cell Biology (2021).

Edit

Researchers reveal the first cryo-EM structures of NSD2 and NSD3 in complex with nucleosome

Phys Dot Org 24 Dec 2020

Genomic DNA wraps around the histone octamer (H2A, H2B, H3, and H4) to form the fundamental unit of chromatin–nucleosome ... Dysregulation of histone lysine methyltransferases has been implicated in various cancers and numerous other diseases. NSD family proteins are specific histone H3 lysine 36 methyltransferases.

Edit

NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B [Biochemistry]

PNAS 01 Dec 2020

... a previously unknown interaction mechanism in histone chaperoning.

Edit

Normal Patterns of Histone H3K27 Methylation Require the Histone Variant H2A.Z in Neurospora crassa [Gene Expression]

Genetics 02 Sep 2020

In mouse embryonic stem cells and multiple plant species, H2A.Z has been found to be ... We report here that Neurospora crassa mutants lacking H2A.Z or SWR-1, the ATP-dependent histone variant exchanger, exhibit a striking reduction in levels of H3K27 methylation.

Edit

Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a ...

PNAS 01 Sep 2020

... histone H2A (γ-H2AX) around a DNA double-strand break (DSB).

Edit

Acetylated histone H4 tail enhances histone H3 tail acetylation by altering their mutual dynamics in ...

PNAS 18 Aug 2020

... and one histone (H3-H4)2 tetramer, wrapped around by ∼146 bp of DNA.

Edit

Normal Patterns of Histone H3K27 Methylation Require the Histone Variant H2A.Z in Neurospora crassa [Investigation]

Genetics 11 Jul 2020

Edit

Silencing the genome with linker histones [Cell Biology]

PNAS 07 Jul 2020

... an octamer of core histone proteins (H2A, H2B, H3, and H4).

Edit

Silencing the genome with linker histones [Commentaries]

PNAS 20 Jun 2020

... an octamer of core histone proteins (H2A, H2B, H3, and H4).

Edit

Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing [Biochemistry]

PNAS 18 Feb 2020

The SWR complex edits the histone composition of nucleosomes at ...

Edit

Tolerance of DNA Replication Stress Is Promoted by Fumarate Through Modulation of Histone Demethylation and ...

Genetics 10 Jul 2019

Fumarase promotes DNA repair by nonhomologous end joining in mammalian cells through interaction with the histone variant H2A.Z, and inhibition of KDM2B, a H3 K36-specific histone demethylase ... stress, and fumarate enhances survival of yeast lacking Htz1p (H2A.Z in mammals).

Edit

35 papers from CSIR-Central Drug Research Institute have manipulated images

The Hindu 04 Jun 2019

A former director of CSIR-IITR Dr. Kailash Chand Gupta and the current director Dr. Alok Dhawan too have papers with such images ... PLoS ONE (2013) ... 13) Nucleosomal histone proteins of L ... a combination of recombinant H2A, H2B, H3 and H4 proteins were highly immunogenic and offered optimum prophylactic efficacy against Leishmania challenge in hamsters.