Techniquest is a Welsh science and discovery centre. It has locations in Cardiff Bay, Glyndŵr University (formerly known as NEWI) in Wrexham, Llanberis in Gwynedd, and the Adventure Centre in Narberth, Pembrokeshire.

Techniquest was first established in Cardiff in 1986. Techniquest gives visitors a hands-on approach to science and includes a science theatre, a planetarium, and a discovery centre.

Techniquest first opened on 13 November 1986 on the site of the old British Gas showroom on the corner of Duke Street and St John Street. There were 48 exhibits at that time, many of them were designed and built by Techniquest. The old showroom was only used as temporary accommodation to house the centre for a couple of months. Less than seven weeks after it had opened Techniquest had welcomed its ten thousandth visitor.

In 1987 they moved to another temporary building opposite the now demolished Welsh Industrial and Maritime Museum in Bute Street. The two buildings were removed to make way for Mermaid Quay.