Donepezil, marketed under the trade name Aricept by its developer Eisai and partner Pfizer, is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the palliative treatment of mild to moderate Alzheimer's disease. Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood–brain barrier. Because it has a half-life of about 70 hours, it can be taken once a day.
Currently, there is no definitive proof that use of donepezil or other similar agents alters the course or progression of Alzheimer's disease. However, 6-12 month controlled studies have shown modest benefits in cognition and/or behavior. Pilot studies have reported that donepezil therapy may potentially have effects on markers of disease progression, such as hippocampal volume. Therefore, many neurologists, psychiatrists, and primary care physicians use donepezil in patients with Alzheimer's disease. In 2005, the UK National Institute for Clinical Excellence (NICE) withdrew its recommendation for use of the drug for mild-to-moderate AD, on the basis that there is no significant improvement in functional outcome, of quality of life, or of behavioral symptoms. However, NICE revised its guidelines to suggest that donepezil be used in moderate stage patients for whom the evidence is strongest. It is currently not licensed for use in the treatment of Alzheimer's disease in the UK at any other stage.
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey
Hey, Mickey
You've been around all night and that's a little long
You think you got the right but I think you got it wrong
Oh, can't you say goodnight so you can take me home, Mickey?
'Cause when you say you will, it always means you won't
You're givin' me the chills, baby, please, baby, don't
Every night you still leave me all alone, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Hey, Mickey
Now if you take me by the, who's ever gonna know?
Every time you move, I let a little more show
There's something you can use so don't say no, Mickey
So come on and give it to me anyway you can
Anyway you wanna do it, I'll take it like a man
Oh, please, baby, please, don't leave me in the damn, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, what a pity you don't understand
You take me by the heart and you take me by the hand
Oh, Mickey, you're so pretty, can't you understand?
It's guys like you, Mickey
And what you do, Mickey, do, Mickey
Don't break my heart, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Hey, Mickey, hey, Mickey
Oh, Mickey, you're so fine
You're so fine, you blow my mind
Pity you,
you're telling me you gotta problem,
a nasty kind of reaction,
a dangerous sword of destruction.
That makes it difficult,
makes it hard to reach
takes it all away,
from what you had in mind.
Yeah yeah yeah
But there's one big fat point
that you seem to be missing.
and it's driving you to distraction,
but doesn't seem to stop you in the least,
or halt this obsession that's got you going back,
Week after week, (week after week)
day after day, (day after day)
hour after hour, (hour after hour)
from where you can
from more the same
You better look out cause
Suspicious eyes are watching
Don't let them see us
I know that you and I
Should not be seen here talking
I kinda like the razor's edge
I always?
You like to walk a tight rope
I work my show without a net
It never fails, I dive
Into the deepest ocean
Not knowing if I'll sink or swim
Oh, oh, over my head, oh, oh
Oh, oh, over my head, oh, oh
We're always meeting in the dark
It's hard to see you
I'll feel my way
I'll take a chance
Risking exposure
Every time I come to meet you
I'm? lady luck again
Oh, oh, over my head, oh, oh
Oh, oh, over my head, oh, oh
I got a feeling
This time I can't take it
You'll play it again
In a place for real
Although I'm falling
So fast already
I'm deeper than I should be
I'm over my head
Oh, oh, over my head, oh, oh
Oh, oh, over my head, oh, oh
Oh, oh, I'm over my head, oh, oh
Oh, oh, over my head, oh, oh
I'm over my head
Oh, oh, over my head, oh, oh
Oh, oh, over my head, oh, oh
Oh, oh, over my head, oh, oh
One...two...three...four!
Foot out the door, I am not a toy
Shoot your rocket outer space
Blast me to the void
I don't need him, time to move my feet.
Lips are on and they're so red
Everything must move ahead
Move on baby desperate
Kickin' like a majorette.
Refrain:
(Oh, did she beat him or knock him off the streets, she go)
(Repeat)
Chorus:
Street beat, she goes walkin' down the street
Street beat, she just knocks them off their feet
Street beat, she goes walkin' out the door
Street beat, she don't want him anymore.
Too many fools, makin' that response
Girl on the string, give him what he wants
I don't need him anymore
To keep me through the shock.
When a person comes today
Tell my man I moved away
When the dog works for his food
Beat them with your attitude.
(Repeat Refrain and Chorus)
(Instrumental)
Bridge:
She's got that street beat
(Repeat 4X with Refrain as counterpoint)
Night on the town, runnin' with the girls
Now that I am free again, it's such a diff'rent world
Fifty eighth or third, fashion's right for me.
Shootin' by a crowded bar
Lowriders in souped-up cars
Don't throw kisses out the door
‘Cause I'm the one who's keepin' score.
(Repeat Refrain & Chorus)
Coda: (Fade)
(Repeat Chorus with Refrain as counterpoint)
(She don't want him anymore)
Heeey Heeey
Hey kid rock n roll
Rock On
Cool my soul
Hey kid boogie too; didn't you
Hey shock summer time blues
jump up and down on my blue suede shoes
He kid rock n roll
Rock On
Where do go from here?
Which is the way that's clear?
Still looking for that blue jean baby queen
pretiest girl I've ever seen. See'em shake
on the movie screen. Jimmy Dean.
Rock On, Rock On, Rock On, Rock On
Hard luck lost and found move on; stick around
making off when the sun goes down, Didn't we?
Hard rock sing the blues; nothing left for us to do.
Money gone what you got to loose?
Rock on
Where do we go from here?
Which is the way that's clear?
Still looking for that blue jean baby queen
pretiest girl I've ever seen. See'em shake
from a movie screen. Jimmy Dean, Jimmy Dean, JD.
Rock On, Rock On, Rock On
Heey Heey, Rock On, Rock On
Heey Heey, Rock On
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
Where do go from here?
Which is the way that's clear?
Where do go from here?
Which is the way that's clear?
Still looking for that blue jean baby queen
pretiest girl I've ever seen. See'em shake
from a movie screen. Jimmy Dean, Jimmy Dean, Jimmy Dean, JD.
Rock On, Rock On, Rock On, Rock On, Rock On
Heey Heey, Rock On, Rock On
Heey Heey, Rock On
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
Rock On kids Rock N Roll Rock on
I had enough
of body stuff
of wearing clothes
and wiping my nose
I give a few, give in to temptation
I just wanna feel every sensation
I'm feeling clean, my experience's my sheen
It takes so much time
to wind and Unwind
From Time to time, I loose my mind (I don't want nobody)
I get so bored, when the guys are gone (I don't want No ONE)
Don't want nobody
Don't want nobody ay ay ay
Don't want nobody
Don't want nobody ay ay ay
Don't want no,
Don't want no,
Don't want no,
Don't want nobody
Don't want no,
Don't want no,
Don't want noooooo,
Don't want nobody
There got to be a Fine Fine Line
between living and dying
I using my body up and I can't deny it
I got to find the fine fine line
I got to know the difference between walking and flying
I lift my hand, to shield my eyes
in my room there's a surprise
Don't want nobody
Don't want nobody ay ay ay
Don't want nobody
Don't want nobody ay ay ay
Don't want no,
Don't want no,
Don't want no,
Don't want nobody
Don't want no,
Don't want no,
Don't want noooooo
Where's that engery coming from?
Can I afford to rest from my fun?
Part of me is leaping, leaping about
Part of me is dying, dying to get out
Don't want nobody
Don't want nobody ay ay ay
Don't want nobody
Don't want nobody ay ay ay
Don't want nobody
Don't want nobody (don't want no)
Don't want nobody (don't want no)
Don't want nobody (don't want no)
Don't want nobody (don't want no)
Don't want nobody (don't want no)
Don't want nobody (don't want no)
Don't want nobody (don't want no)
Don't want nobody (don't want no)
Don't want nobody (don't want no) I
Don't want nobody (don't want no) Don't
Don't want nobody (don't want no) Want
Don't want nobody (don't want no) No
Don't want nobody (don't want no) I
Don't want nobody (don't want no) Don't
Don't want nobody (don't want no) Want
Don't want nobody (don't want no) No
Don't want nobody (don't want no) I
Don't want nobody (don't want no) Don't
Don't want nobody (don't want no) Want
Don't want nobody (don't want no) No
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey, hey Mickey
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey, hey Mickey
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey, hey Mickey
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey
Hey Mickey
You've been around all night, and that's a little long
You think you've got the right, but I think you've got it wrong
Why can't you say goodnight? So you can take me home Mickey?
'Cause when you say you will, it always means you won't
You're givin' me the chills, baby, please, baby don't
Every night you still leave me alone Mickey
Oh Mickey, what a pity, you don't understand
You take me by the heart when you take me by the hand
Oh Mickey, you're so pretty, can't you understand
It's guys like you, Mickey
Oh what you do Mickey, do Mickey,
Don't break my heart, Mickey
Hey Mickey
Now when you take me by the hooves, who's ever gonna know
And every time you move I let a little more show
There's something you can use, so don't say no Mickey
So come on and give it to me anyway you can
Anyway you want to do it, I'll take it like a man
But please baby, please don't leave me in the damp Mickey
Oh Mickey, what a pity, you don't understand
You take me by the heart when you take me by the hand
Oh Mickey, you're so pretty, can't you understand
It's guys like you, Mickey
Oh what you do Mickey, do Mickey,
Don't break my heart, Mickey
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey, hey Mickey
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey, hey Mickey
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey, hey Mickey
Oh Mickey, you're so fine
You're so fine, you blow my mind, hey Mickey
Oh Mickey, what a pity, you don't understand
You take me by the heart when you take me by the hand
Oh Mickey, you're so pretty, can't you understand
It's guys like you, Mickey
Oh what you do Mickey, do Mickey,
Don't break my heart, Mickey
Oh Mickey, what a pity, you don't understand
You take me by the heart when you take me by the hand
Oh Mickey, you're so pretty, can't you understand
It's guys like you, Mickey
Oh what you do Mickey, do Mickey,
Don't break my heart, Mickey
Oh Mickey, what a pity, you don't understand
You take me by the heart when you take me by the hand
Oh Mickey, you're so pretty, can't you understand
It's guys like you, Mickey
Oh what you do Mickey, do Mickey,
Don't break my heart, Mickey
Oh Mickey, what a pity, you don't understand