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Naegleria fowleri ( /nəˈɡlɪəriə/; also known as "the brain-eating amoeba"[citation needed]) is a free-living excavate form of protist typically found in warm bodies of fresh water, such as ponds, lakes, rivers, and hot springs. It is also found in soil, near warm-water discharges of industrial plants, and unchlorinated swimming pools in an amoeboid or temporary flagellate stage. There is no evidence of this organism living in ocean water. It belongs to a group called the Percolozoa or Heterolobosea. It is an amoeba, described as such by the CDC, NCBI, articles on pubmed, and WHO.
N. fowleri can invade and attack the human nervous system. Although this occurs rarely, such an infection nearly always results in the death of the victim. The case fatality rate is estimated at 98%.
Physicians M. Fowler and R. F. Carter first described human disease caused by amebo-flagellates in Australia in 1965. Their work on amebo-flagellates has provided an example of how a protozoan can effectively live both freely in the environment, and in a human host. Since 1965, more than 144 cases have been confirmed in a variety of countries. In 1966, Fowler termed the infection resulting from N. fowleri primary amoebic meningoencephalitis (PAM) in order to distinguish this central nervous system (CNS) invasion from other secondary invasions caused by other true amoebas such as Entamoeba histolytica. A retrospective study determined that the first documented case of PAM possibly occurred in Britain in 1909.