The Cuban National Series (Spanish: Serie Nacional de Béisbol) is the primary domestic amateur baseball competition in Cuba. Formed after the dissolution of the Cuban League in the wake of the Cuban Revolution, the Series is a part of the Cuban national baseball system.

Since 1993, the league has had 16 teams: one representing each province, and two for the city of Havana. Each team is made up of players from the province it represents. In Havana, most of the top tier players take the field for Industriales, traditionally the strongest team in the league. Other typically strong teams include those from Santiago de Cuba, Pinar del Río and Villa Clara.

The 90-game regular season stretches from November until February, and culminates with an eight team tournament to decide the league champion.

Since 2008-2009 championship, the Cuban League has been reorganized - qualification is by zones, and not in groups as it has been the last 15 years.

In the 2011-2012 series, there will be 17 teams, since Havana Province has been split in two new provinces: Artemisa Province and Mayabeque Province. Thus, the Western League will have now 9 teams. The Artemisa team will be nicknamed as "Hunters" (spanish "Cazadores"), and the Mayabeque team as "Hurricanes" (spanish "huracanes").