Leucine (abbreviated as Leu or L) is a branched-chain α-amino acid with the chemical formula HO2CCH(NH2)CH2CH(CH3)2. Leucine is classified as a hydrophobic amino acid due to its aliphatic isobutyl side chain. It is encoded by six codons (UUA, UUG, CUU, CUC, CUA, and CUG) and is a major component of the subunits in ferritin, astacin and other 'buffer' proteins. Leucine is an essential amino acid.
As an essential amino acid, leucine is unable to be synthesised by animals. Consequently, it must be ingested, usually as a component of proteins. In plants and microorganisms, leucine is synthesised from pyruvic acid by a series of enzymes:
Synthesis of the small, hydrophobic amino acid Valine also includes the initial part of this pathway.
Leucine is utilized in the liver, adipose tissue, and muscle tissue. In adipose and muscle tissue, leucine is used in the formation of sterols, and the combined usage of leucine in these two tissues is seven times greater than its use in the liver.
Leucine is the only dietary amino acid that has the capacity to stimulate muscle protein synthesis. As a dietary supplement, leucine has been found to slow the degradation of muscle tissue by increasing the synthesis of muscle proteins in aged rats. While once seen as an important part of the three branch chained amino acids in sports supplements, leucine has since earned more attention on its own as a catalyst for muscle growth and muscular insurance. Supplement companies once marketed the "ideal" 2:1:1 ratio of leucine, iso-leucine and valine; but with furthered evidence that leucine is the most important amino acid for muscle building, it has become much more popular as the primary ingredient in dietary supplements.
I see you move,
It's like memories repeating on me,
And as the sun climbs high,
Spring time has begun for you and me.
The grinding burnt me like a knife,
You're coming home with me tonight,
(Waste no time for talk),
I'm kicking down your bedroom door.
We get to work once inside,
(I won't apologise),
As I feel fire so deep this curtain calls for me.
The start of something new,
These eyes I have are just for you,
Set free this spark,
One night only here we go,
Step one: proceed,
The flames we make will be heard anywhere,
We won't blow out,
Like a candle in the wind.
I see you move,
It's like memories repeating on me,
Under these fiery skies,
You're everything I've dreamed of,
Tonight.
Hold me close, don't let go.
Release this breath you've held so long.
Take my hand, sink like a stone,
Together we turn on and on.
Turn it up, turn me on,
We're starved of air but we ignite.
Strike the match, let it burn,
We're so excited for summer this could be fun.
Now the fuse is lit.
Now the fuse is lit.
Now the fuse is lit.
We had never been introduced,
Tonight I just can’t take my eyes off you.
When I look at you, I could burst into flames,
I’ll follow the rules, but I won’t play any games,
(Entwined, hands clasped tight)
This has got to be the best night I’ve ever had,
(I see potential in your eyes)
You’re a breath of fresh air, a diamond hidden in sand.
You put everyone else I’ve had to shame,
And I couldn’t believe you even knew my name,
(Fight for me) my finest hour,
(In my dreams) it’s in my hands!
We'll have this dance!
Move in shadows, careful to get caught,
See the look their faces, when we head for the door.
A short ride follows this how did I get this far?
But getting you home won’t be the tricky part,
(Entwined, writhe all night)
I have confidence issues that I have to loose,
(Until the first morning light)
So it’s time to impress or there’ll be no round two.
You put everyone else I’ve had to shame,
And I couldn’t believe you even knew my name,
(Fight for me) my finest hour,
(In my dreams) it’s in my hands!
I won’t ask for this kiss that could shatter like glass,
I’ll shed some light on my past, what a delicate attack,
I want more, so I ignore the aching torture I endure
Bite my lip, my heart flips, we’re lying breathless on the floor
I won’t hide away (your exactly what I’m looking for)
Lie here all day (you amaze me, and that’s for sure)
Tomorrow won’t you ring me, come over?
(Tomorrow come over, tomorrow come over)
Tomorrow won’t you ring me, come over?
We thought we could fly.
Breathe in, breathe out,
Because all you ever do is suffocate.
You smell like smoke
And my lungs are so sick of this joke.
Leaves turn brown from green.
I am so bored of this routine.
The air is cold I knew
I would do anything for you.
We thought we could fly
Oh no, oh God,
These stormy seas look to swallow me.
The sky is black.
To break my heart was your attack.
How could you hurt me?
I thought we were friends how wrong could I be?
I've got one over you
Now that I've stolen your perfume.
We thought we could fly
But we fell straight into the ground
Our bodies will not be found
The wind will scatter our ashes.
I miss your breath on the back of my neck,
It's just so hard to accept,
I know I'm not going down gracefully.
We are crashing we're crashing down.
We are crashing we're crashing down.
We are crashing we're crashing down.
We are crashing we're crashing down.
The wind will scatter our ashes.
We thought we could fly
But we fell straight into the ground
Our bodies will not be found
The wind will scatter our ashes.
I miss your breath on the back of my neck,
It's just so hard to accept,
We thought we could fly.
Breathe in, breathe out,
Because all you ever do is suffocate.
You smell like smoke
And my lungs are so sick of this joke.
Leaves turn brown from green.
I am so bored of this routine.
The air is cold I knew
I would do anything for you.
We thought we could fly
Oh no, oh God,
These stormy seas look to swallow me.
The sky is black.
To break my heart was your attack.
How could you hurt me?
I thought we were friends how wrong could I be?
I've got one over you
Now that I've stolen your perfume.
We thought we could fly
But we fell straight into the ground
Our bodies will not be found
The wind will scatter our ashes.
I miss your breath on the back of my neck,
It's just so hard to accept,
I know I'm not going down gracefully.
We are crashing we're crashing down.
We are crashing we're crashing down.
We are crashing we're crashing down.
We are crashing we're crashing down.
The wind will scatter our ashes.
We thought we could fly
But we fell straight into the ground
Our bodies will not be found
The wind will scatter our ashes.
I miss your breath on the back of my neck,
It's just so hard to accept,
Like mountains standing strong and tough,
You are smooth where I am rough.
Proud like sculpture,
In my bedroom we're both digging in nails so hard.
Taste bittersweet, as we treat ourselves tonight,
Smiling graves are lined like teeth stood tight.
And we watch the sky run.
This is my last confession.
I was stone until I met you
(Stand strong through landslides).
Your hand in my hand, we're standing like statues.
We both know that we're to blame
(You make my earthquake).
There's a time and a place but not tonight.
Hard as a rock.
Together we explore these caves,
They might collapse but we are brave,
We turn to dust.
The summer sun will scorch and dry the ground,
In the shade of trees we make no sound.
And we watch the earth turn.
You are my last confession.
I was stone until I met you
(Stand strong through landslides).
Your hand in my hand, we're standing like statues.
We both know that we're to blame
(You make my earthquake).
There's a time and a place but not tonight.
I'd write letters to myself.
I was stone until I met you
(Stand strong through landslides).
Your hand in my hand, we're standing like statues.
We both know that we're to blame
(You make my earthquake).
Oh what a night,
I think as I turn off the light,
And head downstairs, walking backwards in delight,
Your key unlocks the door,
The taxi ride was far too short,
As we get in holding hands, leaving the dancefloor.
And I will follow you where I am lead
Leaving so many things to be left unsaid,
So I talk to you,
And I dance with you.
I buy a drink and then head downstairs,
Where we go through the motions but in reverse,
I un-talk to you,
And un-dance with you.
We sink our last drinks,
The bass booms, the music sings,
(The room spins)
As we get down and dirty dancing, I catch another glimpse,
We talk for hours,
My ears are only yours,
I didn’t catch your name, I ask again, from here the drink pours.
And I will follow you where I am lead
Leaving so many things being left unsaid,
So I talk to you,
And I dance with you.
I buy a drink and then head downstairs,
Where we go through the motions but in reverse,
I un-talk to you,
And un-dance with you.
You make me wanna move
Come home with me tonight, tonight
And this is story that starts at the end,
As soon as we meet I know I intend,
To end up my night in this girls bed,
Otherwise I’m going home instead.
We start to kiss
But not before my,
Hands on her hips,
Notice my target
And that’s where I aim, as I stagger her way,