The Ob River (Russian: Обь), also Obi, is a major river in western Siberia, Russia and is the world's seventh longest river. It is the westernmost of the three great Siberian rivers that flow into the Arctic Ocean (the other two being the Yenisei River and the Lena River). The Gulf of Ob is the world's longest estuary.

The Ob is known to the Khanty people as the As, Yag, Kolta and Yema; to the Nenets people as the Kolta or Kuay; and to the Siberian Tatars as the Umar or Omass.

The Ob forms 16 miles (26 km) southwest of Biysk in Altai Krai at the confluence of the Biya and Katun rivers. Both these streams have their origin in the Altay Mountains, the Biya issuing from Lake Teletskoye, the Katun, 700 kilometres (430 mi) long, bursting out of a glacier on Mount Byelukha.

The river splits into more than one arm, especially after joining the large Irtysh tributary at about 69° E. (Originating in China, the Irtysh is actually longer than the Ob from source to the point of their confluence.) From the source of the Irtysh to the mouth of the Ob, the river flow is the longest in Russia at 5,410 kilometres (3,360 mi). Other noteworthy tributaries are: from the east, the Tom, Chulym, Ket, Tym and Vakh rivers; and, from the west and south, the Vasyugan, Irtysh (with the Ishim and Tobol rivers), and Sosva rivers.

A river is a natural watercourse, usually freshwater, flowing towards an ocean, a lake, a sea, or another river. In a few cases, a river simply flows into the ground or dries up completely before reaching another body of water. Small rivers may also be called by several other names, including stream, creek, brook, rivulet, tributary and rill. There are no official definitions for generic terms, such as river, as applied to geographic features, although in some countries or communities a stream may be defined by its size. Many names for small rivers are specific to geographic location; one example is "burn" in Scotland and northeast England. Sometimes a river is said to be larger than a creek, but this is not always the case, because of vagueness in the language.

Rivers are part of the hydrological cycle. Water within a river is generally collected from precipitation through a drainage basin from surface runoff and other sources such as groundwater recharge, springs, and the release of stored water in natural ice and snowpacks (e.g., from glaciers). Potamology is the scientific study of rivers.