Psilocybin ( /ˌsɪləˈsaɪbɪn/ SIL-ə-SY-bin) is a naturally occurring psychedelic compound produced by more than 200 species of mushrooms, collectively known as psilocybin mushrooms. The most potent are members of the genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens, but psilocybin has also been isolated from about a dozen other genera. As a prodrug, psilocybin is quickly converted by the body to psilocin, which has mind-altering effects similar to those of LSD and mescaline. The effects generally include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, and spiritual experiences, and can include possible adverse reactions such as nausea and panic attacks.

Imagery found on prehistoric murals and rock paintings of modern-day Spain and Algeria suggest that human usage of psilocybin mushrooms dates back thousands of years. In Mesoamerica, the mushrooms had long been consumed in spiritual and divinatory ceremonies before Spanish chroniclers first documented their use in the 16th century. In a 1957 Life magazine article, American banker and ethnomycologist R. Gordon Wasson described his experiences ingesting psilocybin-containing mushrooms during a traditional ceremony in Mexico, introducing the drug to popular culture. Shortly afterward, the Swiss chemist Albert Hofmann isolated the active principle psilocybin from the mushroom Psilocybe mexicana. Hofmann's employer Sandoz marketed and sold pure psilocybin to physicians and clinicians worldwide for use in psychedelic psychotherapy. Although increasingly restrictive drug laws of the late 1960s curbed scientific research into the effects of psilocybin and other hallucinogens, its popularity as an entheogen (spirituality-enhancing agent) grew in the next decade, largely owing to the increased availability of information on how to cultivate psilocybin mushrooms.

Dan Hardy (born May 17, 1982) is an English professional mixed martial artist who competes in the welterweight division. A professional MMA competitor since 2004, Hardy fought in various promotions such as Cage Force and Cage Warriors before signing a contract with the Ultimate Fighting Championship in 2008. He was the final Cage Warriors welterweight and light-welterweight champion. His nickname comes from the screen name he used on the Cage Warrior forum when he was looking for training partners after a disagreement with a coach and his former training partners were forbidden to work with him.

Hardy defeated Akihiro Gono via split decision in his UFC debut at UFC 89. Gono was left swollen and bloody by several of Hardy's left hooks. Gono rocked Hardy on several occasions. In the third round Gono pushed Hardy to the canvas and while there landed an illegal knee to the head of the downed fighter causing the fight to be stopped for a lengthy period and a point deduction for Gono. Hardy recovered and went on to win the split decision. The judges saw the bout 29–28 (twice) for Hardy and 29–28 for Gono.

Ram Dass (born Richard Alpert on April 6, 1931) is an American contemporary spiritual teacher and the author of the seminal 1971 book Be Here Now. He is known for his personal and professional associations with Timothy Leary at Harvard University in the early 1960s, for his travels to India and his relationship with the Hindu guru Neem Karoli Baba, and for founding the charitable organizations Seva Foundation and Hanuman Foundation. He continues to teach via his website.

Alpert was born to a Jewish family in Newton, Massachusetts. His father, George Alpert, was a lawyer in Boston, president of the New York, New Haven and Hartford Railroad, one of the founders of Brandeis University and the Albert Einstein College of Medicine, as well as a major fundraiser for Jewish causes. While Richard did have a bar mitzvah, he was "disappointed by its essential hollowness". He considered himself an atheist and did not profess any religion during his early life, describing himself as “inured to religion. I didn’t have one whiff of God until I took psychedelics.”

William "Bill" Maher, Jr. ( /ˈmɑːr/; born January 20, 1956) is an American stand-up comedian, television host, political commentator, author, and actor. Before his current role as the host of HBO's Real Time with Bill Maher, Maher hosted a similar late-night talk show called Politically Incorrect originally on Comedy Central and later on ABC.

Maher is known for his political satire and sociopolitical commentary, which targets a wide swath of topics including religion, politics, bureaucracies of many kinds, political correctness, the mass media, greed among people and persons in positions of high political and social power, and the lack of intellectual curiosity in the electorate. He supports the legalization of marijuana and same-sex marriage, and serves on the board of PETA. He is also a critic of religion and is an advisory board member of Project Reason, a foundation to promote scientific knowledge and secular values within society. In 2005, Maher ranked at number 38 on Comedy Central's 100 greatest stand-up comedians of all time. Bill Maher received a Hollywood Walk of Fame star on September 14, 2010.

Johns Hopkins (May 19, 1795 – December 24, 1873) was an American entrepreneur, abolitionist and philanthropist of 19th-century Baltimore, Maryland.

His bequests founded numerous institutions bearing his name, including Johns Hopkins Hospital, Johns Hopkins University, Johns Hopkins School of Nursing, Johns Hopkins School of Medicine, and Johns Hopkins Bloomberg School of Public Health.

A biography entitled Johns Hopkins: A Silhouette written by his cousin, Helen Hopkins Thom, was published in 1929 by the Johns Hopkins University Press.

Johns Hopkins was born on May 19, 1795, to Samuel Hopkins (1759–1814) of Anne Arundel County, Maryland, and Hannah Janney (1774–1864), of Loudoun County, Virginia. Home was Whitehall, a 500-acre (two km²) tobacco plantation in Anne Arundel County. His first name derives from a maternal great-grandmother, Margaret Johns, who passed it on to her son.

The Hopkins family were members of the Society of Friends (Quakers). In 1807 they emancipated their slaves in accordance with their local Society decree, which called for freeing the able-bodied and caring for the others, who would remain at the plantation and provide labor as they could. The second eldest of eleven children, 12 year-old Johns was required to work on the farm, interrupting his formal education. From 1806 to 1809, he likely attended The Free School of Anne Arundel County, which was located in today's Davidsonville, Maryland.