The Kingdom of Aksum or Axum, also known as the Aksumite Empire and Abyssinia, was an important trading nation in northeastern Africa, existing from approximately 100–940 AD. It grew from the proto-Aksumite Iron Age period ca. 4th century BC to achieve prominence by the 1st century AD, and was a major player in the commerce between the Roman Empire and Ancient India. The Aksumite rulers facilitated trade by minting their own currency, the state established its hegemony over the declining Kingdom of Kush and regularly entered the politics of the kingdoms on the Arabian peninsula, eventually extending its rule over the region with the conquest of the Himyarite Kingdom.

Under Ezana (fl 320–360), Aksum became the first major empire to convert to Christianity, and was named by Mani (216–276) as one of the four great powers of his time along with Persia, Rome, and China. In the 7th century the Muslims, who originated in Mecca, sought refuge from Quraysh persecution by travelling to Aksum (Abyssinia), a journey famous in Islamic history as the First Hijra. Aksum's ancient capital is found in northern Ethiopia. The Kingdom used the name "Ethiopia" as early as the 4th century. It is also the alleged resting place of the Ark of the Covenant and the purported home of the Queen of Sheba.^{[citation needed]}.

The Kingdom of Kush or Kush was an ancient African state centered on the confluences of the Blue Nile, White Nile and River Atbara in what is now the Republic of Sudan.

Established after the Bronze Age collapse and the disintegration of the New Kingdom of Egypt, it was centered at Napata in its early phase. After king Kashta ("the Kushite") invaded Egypt in the 8th century BC, the Kushite kings ruled as Pharaohs of the Twenty-fifth dynasty of Egypt for a century, until they were expelled by Psamtik I in 656 BC.

During Classical Antiquity, the Kushite imperial capital was at Meroe. In early Greek geography, the Meroitic kingdom was known as Ethiopia. The Kushite kingdom with its capital at Meroe persisted until the 4th century AD, when it weakened and disintegrated due to internal rebellion. The Kushite capital was subsequently captured by the Beja Dynasty, who tried to revive the empire. The Kushite capital was eventually captured and destroyed by the kingdom of Axum. After the collapse of the Kushite empire several states emerged in its former territories, among them Nubia.