The Uppsala Synod in 1593 was the most important synod of the Lutheran Church of Sweden. Sweden had gone through its Protestant Reformation and broken with Roman Catholicism in the 1520s, but an official confession of faith had never been declared.

The synod was summoned to Uppsala by Duke Charles, heir to the Swedish throne. Four bishops and over 300 priests were also present. The synod was opened on March 1, by Nils Göransson Gyllenstierna, and on the following day Nicolaus Olai Bothniensis, a professor of theology at the Uppsala University, was elected chairman.

By March 5, the synod had decided to declare the Holy Scripture the sole guideline for religion. The three creeds—the (Apostles', the Nicene, and the Athanasian)—were officially recognized, and the Lutheran Augsburg Confession (1530) was adopted in its original form.

After the unanimous acceptance of the unaltered Augsburg Confession, Nicolaus Olai Bothniensis, who was presiding, exclaimed, "Now Sweden is one man, and we all have one Lord and God."

Uppsala (Swedish pronunciation: [ˈɵpːˈsɑːla]; older spelling Upsala) is the capital of Uppsala County and the fourth largest city of Sweden. It had 140,454 inhabitants in 2010.

Located 67 km north of the capital, Stockholm, it is also the seat of the Uppsala Municipality. Since 1164, Uppsala has been the ecclesiastical centre of Sweden, being the seat of the Archbishop of the Church of Sweden. Founded in 1477, Uppsala University is the oldest centre of higher education in Scandinavia.

Uppsala was originally located a few kilometres to the north, at a location now known as Gamla Uppsala (Old Uppsala). Today's Uppsala was then called Östra Aros. (Old) Uppsala was, according to medieval writer Adam of Bremen, the main pagan centre of Sweden, and the Temple at Uppsala contained magnificent idols of the Æsir gods.

As a replacement for the Scandinavian gods, Uppsala was made into a strong Christian centre. A bishop was soon consecrated, and in 1164 Uppsala was made into an archdiocese, with Stefan, a monk from Alvastra Abbey, being consecrated the first Archbishop of Uppsala and primate of Sweden.