The São Paulo Metro (Portuguese: Metropolitano de São Paulo, commonly called Metrô) is the principal rapid-transit system in the city of São Paulo and the largest in Brazil. It is also the second largest system in South America and the third largest in Latin America, behind Mexico City and Santiago.

The Companhia do Metropolitano de São Paulo - Metro was founded on 24 April 1968. Eight months later, work on North-South line was initiated. In 1972, the first train trip occurred between Jabaquara and Saúde stations. In 1974, the segment between Jabaquara and Vila Mariana entered into commercial operation.

Today, São Paulo Metro is considered the best rail transportation system in the Americas. The Metro has a length of 74.3 kilometres (46.2 mi), distributed into five lines with 64 stations.

The system is interlinked with CPTM (São Paulo Metropolitan Trains Company) at Brás, Palmeiras-Barra Funda, Tatuapé, Corinthians-Itaquera, Tamanduateí and Santo Amaro stations, and at other modal transportation terminals in the city of São Paulo.^{[dead link]}

São Paulo (/ˌsaʊ ˈpaʊloʊ/; Portuguese pronunciation: [sɐ̃w ˈpawlu] ( listen); Saint Paul;), popularly known as Sampa, is the largest city in Brazil, the largest city in the southern hemisphere and Americas, and the world's seventh largest city by population. The metropolis is anchor to the São Paulo metropolitan area, ranked as the second most populous metropolitan area in the Americas and among the five largest metropolitan areas on the planet. São Paulo is the capital of the state of São Paulo, which is the most populous Brazilian state, and exerts strong regional influence in commerce and finance as well as arts and entertainment. São Paulo maintains strong international influence and is considered an Alpha- World City. The name of the city honors Saint Paul.

The metropolis has significant cultural, economic and political influence both nationally and internationally. It houses several important monuments, parks and museums such as the Latin American Memorial, the Museum of the Portuguese Language, São Paulo Museum of Art and the Ibirapuera Park. The Paulista Avenue is the most important financial center of São Paulo. The city holds many high profile events, like the São Paulo Art Biennial, the Brazil Grand Prix Formula 1 Sao Paulo, Sao Paulo Fashion Week, ATP Brasil Open, and the São Paulo Indy 300.