Djerba (Arabic: جربة‎ Ǧirba), also transliterated as Jerba or Jarbah, is, at 514 km², the largest island of North Africa, located in the Gulf of Gabes, off the coast of Tunisia.

Djerba has a mild climate and a well cultivated soil. Its largest city is Houmt-Souk, with a population of around 65,000. The island is a popular tourist destination, particularly with French, German and Italian tourists, and is known for its beautiful beaches and dramatic sunsets. It is one of the few remaining places in Tunisia where a Berber language is still spoken. Another factor drawing some tourists to Djerba is the 1977 location of the Mos Eisley exterior scenes in the first Star Wars movie, filmed in the town of Ajim.

Djerba is noted as a center of the Islamic sect Al-Ibadhiyah and is also noted for its Jewish minority, which has dwelt on the island for more than 2,500 years, although the Jewish population has declined due to emigration to Israel and France since 1967. Most of the Djerba Jews are Cohanim, descendants of the priestly caste in Judaism, and have maintained this identity for centuries. The El Ghriba synagogue on Djerba is over 2,000 years old and is as such the oldest and one of the most famous in the world.