Fish anatomy is primarily governed by the physical characteristics of water, which is much denser than air, holds a relatively small amount of dissolved oxygen, and absorbs more light than air does.

Fish have a variety of different body plans. Their body is divided into head, trunk, and tail, although the divisions are not always externally visible. The body is often fusiform, a streamlined body plan often found in fast-moving fish. They may also be filiform (eel-shaped) or vermiform (worm-shaped). Also, fish are often either laterally (thin) or dorsally (flat) compressed.

The caudal peduncle is the narrow part of the fish's body to which the caudal or tail fin is attached. The hypural joint is the joint between the caudal fin and the last of the vertebrae. The hypural is often fan-shaped.

Photophores are light-emitting organs which appears as luminous spots on some fishes. The light can be produced from compounds during the digestion of prey, from specialized mitochondrial cells in the organism called photocytes, or associated with symbiotic bacteria, and are used for attracting food or confusing predators.