Adaptive clothing is clothing designed for people with physical disabilities, the elderly, and the infirm who may experience difficulty dressing themselves due to an inability to manipulate closures, such as buttons and zippers, or due to a lack of a full range of motion required for self-dressing. Adaptive clothing typically offers rear-closure designs so that an individual can be dressed more easily by a carer. For example, rather than buttons and zippers, Velcro may be used for garment closures .

Adaptive clothing often addresses such problems as edema, incontenance, and inappropriate undressing issues associated with Alzheimer's disease, Parkinson's disease, or stroke. Adaptive clothing is made for adults and children. Adaptive clothing hallmarks include flat seams to reduce friction, discrete adaptions to make the clothing look as normal as possible, easy access with snaps, velcro and stretchy fabric, roomy seat to accommodate diapers for all ages, longer rise in the back to accommodate sitting in wheelchairs, elastic waist for increased comfort and ease in dressing and meeting safety and flammability standards.