This is a list of major films of 2006.

These are the top grossing films that were first released in 2006. The top ten films of 2006, by worldwide gross in United States dollars, as well as the United States, Canada, United Kingdom, and Australia grosses, are as follows:

In the film industry, a wide-release movie is a film that studios believe will appeal to a broad spectrum of the public and that shows in at least 600 theatres in the United States and Canada. The following films meet these criteria:

Milla Jovovich ( /ˈjoʊvəvɪtʃ/ YOH-və-vich; born Milica Jovović,Serbian Cyrillic: Милица Јововић, Russian: Милица Йовович; December 17, 1975) is an American model, actress, musician, and fashion designer. Over her career, she has appeared in a number of science fiction and action-themed films, for which music channel VH1 has referred to her as the "reigning queen of kick-butt".

Milla Jovovich began modeling when Gene Lemuel convinced Herb Ritts to shoot her for the cover of Lei magazine.Richard Avedon featured her in Revlon's "Most Unforgettable Women in the World" advertisements, and she continued her career with other campaigns for L'Oréal cosmetics, Banana Republic, Christian Dior, Donna Karan, and Versace. In 1988, she had her first professional acting role in the television film The Night Train to Kathmandu, and later that year, she appeared in her first feature film, Two Moon Junction. Following more small television appearances such as the "Fair Exchange" (1989) and a 1989 role as a French girl (she was 14 at the time) on a Married... with Children episode and film roles, she gained notoriety with the romance film Return to the Blue Lagoon (1991). She appeared in 1993's Dazed and Confused, before a short hiatus. Jovovich then acted alongside Bruce Willis in the science fiction film The Fifth Element (1997), and later played the title role in The Messenger: The Story of Joan of Arc (1999). In 2002, she starred in the video game adaptation Resident Evil, which spawned four sequels: Resident Evil: Apocalypse (2004), Resident Evil: Extinction (2007), Resident Evil: Afterlife (2010) and Resident Evil: Retribution (2012).

Nelson Rolihlahla Mandela (Xhosa pronunciation: [xoˈliːɬaɬa manˈdeːla]; born 18 July 1918) is a South African politician who served as President of South Africa from 1994 to 1999, the first ever to be elected in a fully representative democratic election. Before being elected President, Mandela was a militant anti-apartheid activist, and the leader and co-founder of Umkhonto we Sizwe, the armed wing of the African National Congress (ANC). In 1962 he was arrested and convicted of sabotage and other charges, and sentenced to life imprisonment. Mandela went on to serve 27 years in prison, spending many of these years on Robben Island. Following his release from prison on 11 February 1990, Mandela led his party in the negotiations that led to the establishment of democracy in 1994. As President, he frequently gave priority to reconciliation, while introducing policies aimed at combating poverty and inequality in South Africa.

In South Africa, Mandela is often known as Madiba, his Xhosa clan name; or as tata (Xhosa: father). Mandela has received more than 250 awards over four decades.

Saif Ali Khan (pronounced [ˈsɛːf əˈli ˈxaːn]; born 16 August 1970) is an Indian actor known for his work in Bollywood films. He is the son of the cricket player and last titular Nawab of Pataudi, late Mansoor Ali Khan Pataudi, and actress Sharmila Tagore, a great-grandniece of poet Rabindranath Tagore.

Having made his acting debut in 1992 with Parampara, Khan had his first success with the 1994 films Main Khiladi Tu Anari and Yeh Dillagi. After going through several years of decline throughout the 1990s, he rose into prominence with his performance in Dil Chahta Hai (2001), which marked his professional turning point. His work in Kal Ho Naa Ho (2003) won him the Filmfare Award for Best Supporting Actor, and he was awarded the National Film Award for Best Actor for his performance in Hum Tum (2004).

Khan subsequently had further mainstream success with films like Salaam Namaste (2005) and Race (2008) and starred in critically acclaimed projects such as Parineeta (2005), Being Cyrus and Omkara (2006). In 2009, Khan branched out into film production with his company Illuminati Films' first film Love Aaj Kal, which became a box-office success. These accomplishments have established him as one of the leading actors of Hindi cinema. He was awarded the Padma Shri civilian award by the Government of India in 2010.

Sacha Noam Baron Cohen (born 13 October 1971) is an English stand-up comedian, writer, actor, and voice actor. A graduate of Cambridge University, Baron Cohen is most widely known for writing and playing four unorthodox fictional characters: Ali G, Borat, Brüno, and Admiral General Aladeen. In his routines, Baron Cohen's characters interact with unsuspecting people who do not realise they are being set up for comic situations and self-revealing ridicule.

Baron Cohen was named Best Newcomer at the 1999 British Comedy Awards for The 11 O'Clock Show, and since then, his work has been further recognised with two BAFTA Awards for Da Ali G Show, several Emmy nominations, a nomination for an Academy Award for Writing Adapted Screenplay, and a Golden Globe for Best Actor for his work in the feature film Borat: Cultural Learnings of America for Make Benefit Glorious Nation of Kazakhstan. After the release of Borat, Baron Cohen stated that because the public had become too familiar with the characters, he would retire Borat and Ali G. Similarly, after the release of Brüno, Baron Cohen has stated he would also retire the title character.